Evidence map›Paper›PMID 34232513›Full record

ArticleJournal of medical virology2021

Emergence of a young case infected with avian influenza A (H5N6) in Anhui Province, East China during the COVID-19 pandemic.

Jun-Ling Yu, Sai Hou, Ya-Ting Feng, Ge Bu, Qing-Qing Chen, Zhao-Qian Meng, Zhen-Tao Ding, Liang-Zi Guo, Xue Zhou, Meng Wang and 9 more

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 2 countries.

Jun-Ling YuMicrobiological Laboratory, Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui, China.
Sai HouMicrobiological Laboratory, Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui, China.
Ya-Ting FengDepartment of Epidemiolgy and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Ge BuMicrobiological Laboratory, Fuyang City Center for Disease Control and Prevention, Fuyang, Anhui, China.
Qing-Qing ChenMicrobiological Laboratory, Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui, China.
Zhao-Qian MengMicrobiological Laboratory, Fuyang City Center for Disease Control and Prevention, Fuyang, Anhui, China.
Zhen-Tao DingMicrobiological Laboratory, Fuyang City Center for Disease Control and Prevention, Fuyang, Anhui, China.
Liang-Zi GuoMicrobiological Laboratory, Fuyang City Center for Disease Control and Prevention, Fuyang, Anhui, China.
Xue ZhouMicrobiological Laboratory, Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui, China.
Meng WangMicrobiological Laboratory, Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui, China.
Xin-Er HuangDepartment of Epidemiolgy and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Wei-Wei LiMicrobiological Laboratory, Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui, China.
Lan HeMicrobiological Laboratory, Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui, China.
Lei GongMicrobiological Laboratory, Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui, China.
Yong SunMicrobiological Laboratory, Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui, China.
Zhiwei XuSchool of Public Health, Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia.
Hai-Feng PanDepartment of Epidemiolgy and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.ORCID 0000-0001-8218-5747
Jun HeMicrobiological Laboratory, Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui, China.
Jia-Bing WuMicrobiological Laboratory, Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui, China.
Anhui Provincial Center for Disease Control and Prevention · CNFuyang Second People's Hospital · CNAnhui Medical University · CNQueensland Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the context of the coronavirus disease 2019 pandemic, we investigated the epidemiological and clinical characteristics of a young patient infected by avian influenza A (H5N6) virus in Anhui Province, East China, and analyzed genomic features of the pathogen in 2020. Through the cross-sectional investigation of external environment monitoring (December 29-31, 2020), 1909 samples were collected from Fuyang City. It was found that the positive rate of H5N6 was higher than other areas obviously in Tianma poultry market, where the case appeared. In addition, dual coinfections were detected with a 0.057% polymerase chain reaction positive rate the surveillance years. The virus was the clade 2.3.4.4, which was most likely formed by genetic reassortment between H5N6 and H9N2 viruses. This study found that the evolution rates of the hemagglutinin and neuraminidase genes of the virus were higher than those of common seasonal influenza viruses. The virus was still highly pathogenic to poultry and had a preference for avian receptor binding.

Indexed as

AnimalsChild, PreschoolChinaCOVID-19FemaleGenome, ViralHumansInfluenza A virusInfluenza, HumanInfluenza in BirdsMutationPhylogenyPoultryReassortant VirusesSARS-CoV-2Viral ProteinsViral ProteinsCOVID-19epidemiologygeneticH5N6

Identifiers

PMID34232513
PMCPMC8426836
OpenAlexW3180203582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.