Evidence map›Paper›PMID 34232452›Full record

Trial reportJournal of community health2022

A Multilevel Intervention to Increase HPV Vaccination among Asian American Adolescents.

Grace X Ma, Lin Zhu, Yin Tan, Shumenghui Zhai, Timmy R Lin, Cristina Zambrano, Philip Siu, Sarah Lai, Min Qi Wang

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of community health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07637630 (Applying the Multiphase Optimization Strategy to Develop and Test a Culturally-Relevant Digital Health Intervention Targeting HPV Vaccination Among U.S. Vietnamese), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07637630 narecruitingnot on this mapstarted 2026, after this paper: background citation

Applying the Multiphase Optimization Strategy to Develop and Test a Culturally-Relevant Digital Health Intervention Targeting HPV Vaccination Among U.S. Vietnamese

TypeinterventionalSponsorNorthwestern UniversityRan2026 to 2029Enrolled96ConditionsHPV-related Cancers, HPV VaccinationArmsExpert Video, Self-persuasion, Narrative Storytelling, Motivational Interviewing, Constant Component
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. U.S. Vietnamese Parents' Perceptions of Different Approaches for Confirming Adolescent HPV Vaccination Records in Research Studies.Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Grace X MaCenter for Asian Health, Lewis Katz School of Medicine, Temple University, 3440 N. Broad Street, Philadelphia, PA, 19140, USA. grace.ma@temple.edu.ORCID 0000-0002-3619-0550
Lin ZhuCenter for Asian Health, Lewis Katz School of Medicine, Temple University, 3440 N. Broad Street, Philadelphia, PA, 19140, USA.
Yin TanCenter for Asian Health, Lewis Katz School of Medicine, Temple University, 3440 N. Broad Street, Philadelphia, PA, 19140, USA.
Shumenghui ZhaiCenter for Asian Health, Lewis Katz School of Medicine, Temple University, 3440 N. Broad Street, Philadelphia, PA, 19140, USA.
Timmy R LinCenter for Asian Health, Lewis Katz School of Medicine, Temple University, 3440 N. Broad Street, Philadelphia, PA, 19140, USA.
Cristina ZambranoHunter College Center for Cancer Health Disparities Research, 695 Park Avenue, New York, NY, 10065, USA.
Philip SiuGreater Philadelphia Health Action, Inc., 432 N 6th St, Philadelphia, PA, 19123, USA.
Sarah LaiGreater Philadelphia Health Action, Inc., 432 N 6th St, Philadelphia, PA, 19123, USA.
Min Qi WangSchool of Public Health, University of Maryland, 4200 Valley Dr, College Park, MD, 20742, USA.
Temple University · USResearch for Action · USHunter College · USTemple University Health System · USUniversity of Maryland, College Park · US

Funding

TUFCCC/HC Regional Comprehensive Cancer Health PartnershipU54CA221705 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI Yin Tan · 2018 to 2026
$16.3M
Training ProgramU54CA153513 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI MA, GRACE X. · 2010 to 2015
$5.2M
NCI NIH HHS U54 CA153513NCI NIH HHS U54 CA221705
6 · The paper itself

Abstract

Human papillomavirus (HPV) is the most common sexually transmitted infection in the US. HPV vaccine is a viable source of prevention against high-risk strains that are likely to cause cancer. However, particularly among racial and ethnic minorities such as Chinese Americans, HPV vaccination rates are suboptimal. The goal of this study was to evaluate the effect of a culturally tailored intervention on HPV vaccine uptake in Chinese Americans. We designed and implemented a multilevel longitudinal pilot study to examine the efficacy of the HPV intervention among Chinese American parents/guardians. We recruited 180 participants from federally qualified health center and community-based clinics that serve predominantly low-income Chinese Americans in Philadelphia. Participants were randomized into an intervention group (n = 110) or a control group (n = 70). The intervention group received an HPV specific intervention, while the control group received a general health intervention. The primary outcome was medical record-confirmed receipt of first shot and completion of HPV vaccine within six months of receiving the interventions. Repeated measure ANOVA was utilized to examine the intervention effect on knowledge between intervention and control groups. Knowledge differed significantly, with participants in the intervention group demonstrating the greatest improvement following the intervention. A multivariable logistic regression was used to examine the association between HPV vaccine initiation and study group assignment. There was a significant effect of provider recommendation, parent's gender, and health insurance status on HPV vaccine uptake. This study demonstrated positive impact of a culturally tailored intervention on HPV vaccination uptake among Chinese Americans.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesAdolescentAsianHealth Knowledge, Attitudes, PracticeHumansPilot ProjectsVaccinationPapillomavirus VaccinesChinese American adolescentsCommunity-based participatory researchHuman papillomavirusVaccination

Identifiers

PMID34232452
PMCPMC8738771
OpenAlexW3180251412

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.