Evidence map›Paper›PMID 34232408›Full record

ArticleNeurosurgical review2022

Odontoid Type II fractures in elderly: what are the real management goals and how to best achieve them? A multicenter European study on functional outcome.

Salvatore Chibbaro, Charles-Henry Mallereau, Mario Ganau, Ismail Zaed, Maria Teresa Bozzi, Antonino Scibilia, Helene Cebula, Irene Ollivier, Marie-Pierre Loit, Dominique Chaussemy and 12 more

Open access · greenAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Neurosurgical review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Anterior Odontoid Screw Fixation: Current Advances in Indications and Techniques.Advances and technical standards in neurosurgery · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. [Treatment of geriatric odontoid fractures].Unfallchirurgie (Heidelberg, Germany) · 2025
    Article
  6. Review
  7. Article
  8. Trends in management of odontoid fractures 2010-2021.North American Spine Society journal · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 10 institutions in 4 countries.

Salvatore ChibbaroDepartment of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.
Charles-Henry MallereauDepartment of Neurosurgery, Strasbourg University Hospital, Strasbourg, France. Mallereau.charles@gmail.com.ORCID http://orcid.org/0000-0002-8747-7332
Mario GanauDepartment of Neurosurgery, Oxford University Hospital, Oxford, UK.
Ismail ZaedDepartment of Neurosurgery, Humanitas University Hospital, Rozzano, Italy.
Maria Teresa BozziDepartment of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.
Antonino ScibiliaDepartment of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.
Helene CebulaDepartment of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.
Irene OllivierDepartment of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.
Marie-Pierre LoitDepartment of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.
Dominique ChaussemyDepartment of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.
Hugo-Andres CocaDepartment of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.
Guillaume DannhoffDepartment of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.
Antonio RomanoDepartment of Neurosurgery, Parma University Hospital, Parma, Italy.
Beniamino NannavecchiaDepartment of Neurosurgery, Teramo Hospital, Teramo, Italy.
Arthur GubianDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Giorgio SpatolaDepartment of Neurosurgery, Poli-Ambulanza Hospital, Brescia, Italy.
Francesco SignorelliDepartment of Neurosurgery, Bari University Hospital, Bari, Italy.
Corrado IaccarinoDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Raoul PopNeuroradiology Unit, Strasbourg University Hospital, Strasbourg, France.
François ProustDepartment of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.
Seyyid BalogluNeuroradiology Unit, Strasbourg University Hospital, Strasbourg, France.
Julien TodeschiDepartment of Neurosurgery, Strasbourg University Hospital, Strasbourg, France.
Université de Strasbourg · FRFondazione Poliambulanza Istituto Ospedaliero · ITHeidelberg University · DEHôpital Civil, Strasbourg · FRHumanitas University · ITUniversity of Bari Aldo Moro · ITUniversity of Modena and Reggio Emilia · ITUniversity of Oxford · GBUniversity of Parma · ITUniversity of Teramo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Odontoid fractures constitute the most common cervical fractures in elderly. External immobilization is the treatment of choice for Type I and III; there is still no wide consensus about the best management of Type II fractures. Observational multicenter study was conducted on a prospectively built database on elderly patients (> 75 years) with Type II odontoid fracture managed conservatively during the last 10 years. All patients underwent CT scan on admission and at 3 months; if indicated, selected patient had CT scan at 6 and 12 months. All patients were clinically evaluated by Neck Disability Index (NDI), Charlson Comorbidity Index (CCI), and American Society of Anaesthesiologists classification (ASA) on admission; NDI was assessed also at 6 weeks, 3, 6, 12, and 24 months; furthermore, a quality of life (QoL) assessment with the SF-12 form was performed at 3 and 12 months. Among the 260 patients enrolled, 177 (68%) were women and 83 (32%) men, with a median age of 83 years. Patients were followed up for a minimum of 24 months: 247 (95%) showed an excellent functional outcome within 6 weeks, among them 117 (45%) showed a good bony healing, whereas 130 (50%) healed in pseudo-arthrosis. The residual 5% were still variably symptomatic at 12 weeks; however, only 5 out of 13 (2% of the total cohort) required delayed surgery. This study showed that a conservative approach to odontoid Type II fracture in elderly is an effective and valid option, resulting in an excellent functional outcome (regardless of bony fusion) in the majority of cases. Failure of conservative treatment can be safely addressed with surgical fixation at a later stage.

Indexed as

Odontoid ProcessSpinal FracturesAgedAged, 80 and overFemaleGoalsHumansMaleQuality of LifeRetrospective StudiesTreatment OutcomeConservative managementElderlyExternal immobilizationFunctional outcomeSurgeryType II odontoid fracture

Identifiers

PMID34232408
OpenAlexW3181383229

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.