Evidence map›Paper›PMID 34232353›Full record

ArticleWorld journal of urology2021

Safety and efficacy of TURP vs. laser prostatectomy for the treatment of benign prostatic hyperplasia in multi-morbid and elderly individuals aged ≥ 75.

David Bouhadana, David-Dan Nguyen, Xinyan Zhang, Jialin Mao, Dean S Elterman, Alexis E Te, Kevin C Zorn, Naeem Bhojani, Art Sedrakyan, Bilal Chughtai

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Safety and clinical outcomes of GreenLight laser prostatectomy in octogenarians.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
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  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

David BouhadanaFaculty of Medicine, McGill University, Montreal, QC, Canada.
David-Dan NguyenFaculty of Medicine, McGill University, Montreal, QC, Canada.
Xinyan ZhangDepartment of Healthcare Policy and Research, Weill Cornell Medical College-New York Presbyterian, New York, NY, USA.
Jialin MaoDepartment of Healthcare Policy and Research, Weill Cornell Medical College-New York Presbyterian, New York, NY, USA.
Dean S EltermanDivision of Urology, Dept. of Surgery, University Health Network, University of Toronto, Toronto, ON, Canada.
Alexis E TeDepartment of Urology, Weill Cornell Medical College/New York Presbyterian, 425 East 61st St., 12th Floor, New York, NY, 10065, USA.
Kevin C ZornDivision of Urology, Centre hospitalier de l'Université de Montréal, Montreal, QC, Canada.
Naeem BhojaniDivision of Urology, Dept. of Surgery, University Health Network, University of Toronto, Toronto, ON, Canada.
Art SedrakyanDepartment of Healthcare Policy and Research, Weill Cornell Medical College-New York Presbyterian, New York, NY, USA.
Bilal ChughtaiDepartment of Urology, Weill Cornell Medical College/New York Presbyterian, 425 East 61st St., 12th Floor, New York, NY, 10065, USA. bic9008@med.cornell.edu.ORCID http://orcid.org/0000-0002-0515-2578
Cornell University · USMcGill University · CAUniversity Health Network · CACentre Hospitalier de l’Université de Montréal · CANewYork–Presbyterian Hospital · US

Funding

FDA HHS U01 FD006936
6 · The paper itself

Abstract

purposeTo compare the safety and durability of transurethral resection of the prostate (TURP) and Laser prostatectomy (LP) among multi-morbid and elderly patients.

methodsUsing data retrieved from the New York State Department of Health Statewide Planning and Research Cooperative System and the California Office of Statewide Health Planning and Development, we selected cohorts of 1) multi-morbid (Charlson comorbidity index ≥ 3) and 2) elderly (aged ≥ 75) patients with benign prostatic hyperplasia who underwent laser coagulation, vaporization, enucleation, or TURP between January 2005 and December 2016. We assessed the post-operative incidence of hospital readmission and ER visit at 30 days and 90 days, complications at 90 days, and reoperation and the development of urethral stricture at 6 months or longer.

resultsWe found 12,815 and 29,806 patients in the multi-morbid and elderly cohort, respectively. Compared to LP, TURP was associated with lower odds of 90-day hospital readmission and ER visit in the multi-morbid cohort (OR 0.92, 95% CI 0.85-1.00) and higher odds in the elderly cohort (OR 1.07, 95% CI 1.01-1.14). The multi-morbid cohort showed lower odds of urinary tract infections (Ref: LP, OR 0.83, 95% CI 0.73-0.93). The elderly cohort showed higher odds of experiencing hematuria (OR 1.28, 95% CI 1.03-1.59) post TURP. TURP was associated with a 19% (95% CI 0.66-1.00) and 20% (95% CI 0.71-0.91) reduced hazard of reoperation at 6 months or longer for multi-morbid and elderly cohorts, respectively.

conclusionCompared to LP, TURP was associated with higher complication rates for the multi-morbid and elderly cohorts overall but a lower hazard of reoperation, supporting its durability.

Indexed as

AgedAged, 80 and overAge FactorsHumansLaser TherapyMaleProstatectomyProstatic HyperplasiaRetrospective StudiesTransurethral Resection of ProstateTreatment OutcomeBenign prostatic hyperplasiaLaser prostatectomyLower urinary tract symptomsTransurethral resection of the prostate

Identifiers

PMID34232353
OpenAlexW3179287994

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.