Evidence map›Paper›PMID 34232279›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2021

Age, Sex, and Inhibitory Control: Identifying a Specific Impairment in Memorial, But Not Perceptual, Inhibition in Older Women.

Alexander L M Siegel, Teal S Eich

Open access · bronzeAbstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexander L M SiegelThe Davis School of Gerontology, University of Southern California, Los Angeles, California, USA.
Teal S EichThe Davis School of Gerontology, University of Southern California, Los Angeles, California, USA.ORCID 0000-0003-4094-3276
University of Southern California · US

Funding

Exploring Cognitive Aging Using Reference Ability Neural NetworksR01AG038465 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HABECK, CHRISTIAN GEORG, STERN, YAAKOV · 2011 to 2025
$17.0M
RESEARCH TRAINING IN GERONTOLOGYT32AG000037 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE, EILEEN M CRIMMINS · 1985 to 2026
$13.2M
Imaging of Cognition, Learning and Memory in AgingR01AG026158 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STERN, YAAKOV · 2004 to 2021
$10.9M
Exploring the Latent Class Structure of Inhibition in Normal AgingR00AG055684 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI EICH, TEAL S · 2019 to 2021
$741k
Exploring the Latent Class Structure of Inhibition in Normal AgingK99AG055684 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EICH, TEAL S · 2017 to 2018
$260k
NIA NIH HHS K99 AG055684NIA NIH HHS R00 AG055684NIA NIH HHS R00AG055684NIA NIH HHS R01 AG026158NIA NIH HHS R01 AG038465NIA NIH HHS T32 AG000037
6 · The paper itself

Abstract

objectivesDeclines in the ability to inhibit information, and the consequences to memory of unsuccessful inhibition, have been frequently reported to increase with age. However, few studies have investigated whether sex moderates such effects. Here, we examined whether inhibitory ability may vary as a function of age and sex, and the interaction between these two factors.

method202 older (mean age = 69.40 years) and younger (mean age =30.59 years) participants who had equivalent educational attainment and self-reported health completed 2 tasks that varied only in the time point at which inhibition should occur: either prior to, or after, encoding.

resultsWhile we did not find evidence for age or sex differences in inhibitory processes when information needed to be inhibited prior to encoding, when encoded information being actively held in working memory needed to be suppressed, we found that older women were particularly impaired relative to both younger women and men of either age group. DISCUSSION: These results provide further support for the presence of memorial inhibitory deficits in older age, but add nuance by implicating biological sex as an important mediator in this relationship, with it more difficult for older women to inhibit what was once relevant in memory.

Indexed as

AgingMemory, Short-TermProactive InhibitionReactive InhibitionSex FactorsAdultAgedAge FactorsFemaleHumansIndependent LivingMaleNeuropsychological TestsReaction TimeSelf-ControlAgingControlInhibitionSexWorking memory

Identifiers

PMID34232279
PMCPMC8599043
OpenAlexW3178527768

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.