SynthesisMedicine2021
Financial burden of postoperative complications following colonic resection: A systematic review.
Synthesis in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic impact of myosteatosis on postoperative outcomes and survival in colorectal cancer: a systematic review.International journal of colorectal disease · 2026Pooled it
- Preoperative Weight Loss in Patients With Excess Weight and Colorectal Cancer: The CARE Feasibility Randomized Clinical Trial.JAMA network open · 2025Trial
- Article
- Macrophages in Intestinal Wound Healing: Dichotomous Effects and Therapeutic Opportunities.International journal of molecular sciences · 2026Review
- Oncologic standards in colon cancer resection: from margins to lymph node yield and mesentery.Frontiers in surgery · 2026Review
- Review
- Over-the-scope clip for postsurgical anastomotic dehiscence and bleeding.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2025Article
- Procalcitonin and C-reactive protein as early markers of anastomotic leakage in intestinal resections for advanced ovarian cancer (EDMOCS).Acta obstetricia et gynecologica Scandinavica · 2024Observational
- The hospital costs of complications following major abdominal surgery: a retrospective cohort study.BMC research notes · 2024Article
- Wearable Sensors as a Preoperative Assessment Tool: A Review.Sensors (Basel, Switzerland) · 2024Review
- Quantifying societal burden of radiation-induced small bowel toxicity in patients with rectal cancer.Frontiers in oncology · 2024Article
- Impact of surgical complications on hospital costs and revenues: retrospective database study of Medicare claims.Journal of comparative effectiveness research · 2023Article
- All-cause 30- and 90-day inpatient readmission costs associated with 4 minimally invasive colon surgery approaches: A propensity-matched analysis using Medicare and commercial claims data.Surgery open science · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundColonic resection is a common surgical procedure that is associated with a high rate of postoperative complications. Postoperative complications are expected to be major contributors to hospital costs. Therefore, this systematic review aims to outline the health costs of postoperative complications following colon resection surgery.
methodsMEDLINE, Excerpta Medica database, Cochrane, and Economics literature medical databases were searched from 2010 to 2019 to identify English studies containing an economic evaluation of postoperative complications following colonic resection in adult patients. All surgical techniques and indications for colon resection were included. Eligible study designs included randomized trials, comparative observational studies, and conference abstracts.
resultsThirty-four articles met the eligibility criteria. We found a high overall complication incidence with associated increased costs ranging from $2290 to $43,146. Surgical site infections and anastomotic leak were shown to be associated with greater resource utilization relative to other postoperative complications. Postoperative complications were associated with greater incidence of hospital readmission, which in turn is highlighted as a significant financial burden. Weak evidence demonstrates increased complication incidence and costlier complications with open colon surgery as compared to laparoscopic surgery. Notably, we identified a vast degree of heterogeneity in study design, complication reporting and costing methodology preventing quantitative analysis of cost results.
conclusionsPostoperative complications in colonic resection appear to be associated with a significant financial burden. Therefore, large, prospective, cost-benefit clinical trials investigating preventative strategies, with detailed and consistent methodology and reporting standards, are required to improve patient outcomes and the cost-effectiveness of our health care systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.