Evidence map›Paper›PMID 34232111›Full record

ArticleBioengineered2021

Long non-coding RNA CRNDE regulates the growth and migration of prostate cancer cells by targeting microRNA-146a-5p.

Dewang Fu, Li'e Zang, Zhaowei Li, Chenghui Fan, Huamao Jiang, Tongyi Men

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. CRNDE: A Pivotal Oncogenic Long Non-Coding RNA in Cancers.The Yale journal of biology and medicine · 2023
    Review
  5. Noncoding RNAs improve the predictive power of network medicine.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Dewang FuDepartment of Urology Surgery, Shandong Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Li'e ZangDepartment of Urology Surgery, The First Affiliate Hospital of Jinzhou Medical University, Jinzhou, China.
Zhaowei LiDepartment of Urology Surgery, The First Affiliate Hospital of Jinzhou Medical University, Jinzhou, China.
Chenghui FanDepartment of Urology Surgery, The First Affiliate Hospital of Jinzhou Medical University, Jinzhou, China.
Huamao JiangDepartment of Urology Surgery, The First Affiliate Hospital of Jinzhou Medical University, Jinzhou, China.
Tongyi MenDepartment of Urology Surgery, Shandong Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
First People's Hospital of Jingzhou · CNJinzhou Medical University · CNShandong Provincial QianFoShan Hospital · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The function of lncRNA CRNDE and its role in prostate cancer (PC) remains unclear. The aim of this study was to determine the expression level of lncRNA CRNDE in PC tissues and to elucidate its role in PC. The expression levels of lncRNA CRNDE were measured by quantitative reverse transcription polymerase chain reaction. The role of lncRNA CRNDE in PC cells was studied using loss-of-function assays

Indexed as

ApoptosisBase SequenceCell Line, TumorCell MovementCell ProliferationDown-RegulationGene Expression Regulation, NeoplasticGene Knockdown TechniquesHumansMaleMatrix Metalloproteinase 2Matrix Metalloproteinase 9MicroRNAsNeoplasm InvasivenessProstatic NeoplasmsRNA, Long NoncodingCRNDE RNA, humanMatrix Metalloproteinase 2Matrix Metalloproteinase 9MicroRNAsMIRN146 microRNA, humanRNA, Long NoncodingRNA, Small InterferinglncRNA crndemiR-146a-5pProstate cancer

Identifiers

PMID34232111
PMCPMC8806644
OpenAlexW3180950166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.