ArticleJournal of the American Chemical Society2021
Direct Synthesis of Enamides via Electrophilic Activation of Amides.
Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Carbonylative Aminative Suzuki-Miyaura Coupling: Pd-Catalyzed Synthesis of Amides from Vinyl/Aryl Halides and Boronic Acids.Journal of the American Chemical Society · 2026Article
- Photoredox-Catalyzed Lysine C(spJournal of the American Chemical Society · 2026Article
- Regiodivergent α- and β-Functionalization of SaturatedJournal of the American Chemical Society · 2025Article
- Pyrrolidine synthesis via ring contraction of pyridines.Nature communications · 2025Article
- α,β-Desaturation and Formal β-C(spJournal of the American Chemical Society · 2024Article
- A facile synthesis of α,β-unsaturated imines via palladium-catalyzed dehydrogenation.Nature communications · 2024Article
- A Neutral PCThe Journal of organic chemistry · 2024Article
- Cobalt-catalyzed double hydroboration of pyridines.Chemical science · 2024Article
- Coordinating activation strategy enables 1,2-alkylamidation of alkynes.Chemical science · 2023Article
- Challenges and Breakthroughs in Selective Amide Activation.Angewandte Chemie (International ed. in English) · 2022Review
- Challenges and Breakthroughs in Selective Amide Activation.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2022Review
- A three-component difunctionalization ofChemical communications (Cambridge, England) · 2022Article
- Selective desaturation of amides: a direct approach to enamides.Chemical science · 2022Article
- γ C-H Functionalization of Amines via Triple H-Atom Transfer of a Vinyl Sulfonyl Radical Chaperone.Journal of the American Chemical Society · 2022Article
- Cobalt-catalyzed chemoselective dehydrogenation through radical translocation under visible light.Chemical science · 2022Article
- Remote Radical Desaturation of Unactivated C-H Bonds in Amides.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
A novel, one-step N-dehydrogenation of amides to enamides is reported. This reaction employs the unlikely combination of LiHMDS and triflic anhydride, which serves as both the electrophilic activator and the oxidant, and is characterized by its simple setup and broad substrate scope. The synthetic utility of the formed enamides was readily demonstrated in a range of downstream transformations.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.