ReviewClinics (Sao Paulo, Brazil)2021
Extrapulmonary onset manifestations of COVID-19.
Review in Clinics (Sao Paulo, Brazil), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 44 citations in OpenAlex.
- Impact of Early COVID-19 Antiviral Therapy on the Incidence of Uveitis: A Retrospective Cohort Study Using the TriNetX Database.Immunity, inflammation and disease · 2026Observational
- If Status Epilepticus Disappears with Tocilizumab, Paucisymptomatic SARS-CoV-2 Infection Should Be Suspected.Internal medicine (Tokyo, Japan) · 2025Article
- To: Identification of distinct phenotypes and improving prognosis using metabolic biomarkers in COVID-19 patients.Critical care science · 2025Article
- Calibration of Prediction Models of In-hospital Mortality in SARS-CoV-2 Patients Depends also on Data Quality.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- The impact of inflammatory and metabolic markers on depression, anxiety, and cognition after COVID-19: a narrative review.Trends in psychiatry and psychotherapy · 2024Review
- Prospective studies are required for assessing the outcome of a SARS-CoV-2 infection based on the symptoms at onset.The Libyan journal of medicine · 2023Article
- Pathomorphological Features of the Novel Coronavirus Disease in Patients with Systemic Amyloidosis.Biomedicines · 2023Article
- Article
- Care home SARS-CoV-2 outbreaks are highly dependent on the immunocompetence of the infected people.The Journal of hospital infection · 2023Article
- COVID-19 Biomarkers at the Crossroad between Patient Stratification and Targeted Therapy: The Role of Validated and Proposed Parameters.International journal of molecular sciences · 2023Review
- Potential for Early Noninvasive COVID-19 Detection Using Electronic-Nose Technologies and Disease-Specific VOC Metabolic Biomarkers.Sensors (Basel, Switzerland) · 2023Review
- Comparison of systemic inflammatory profiles in COVID-19 and community-acquired pneumonia patients: a prospective cohort study.Respiratory research · 2023Observational
- COVID-19 immunopathology: From acute diseases to chronic sequelae.Journal of medical virology · 2023Review
- Inflammatory markers as outcome predictors of COVID-19 in pregnant women.Revista da Associacao Medica Brasileira (1992) · 2023Article
- Opsoclonus Myoclonus Ataxia Syndrome Due to SARS-CoV-2.Neuro-ophthalmology (Aeolus Press) · 2023Review
- SARS-CoV-2 down-regulates ACE2 through lysosomal degradation.Molecular biology of the cell · 2022Article
- Facial Pressure Sores in COVID-19 Patients during Prone Positioning: A Case Series and Literature Review.Plastic and reconstructive surgery. Global open · 2022Article
- Outcome of SARS-CoV-2 associated Guillain-Barre syndrome depends on early treatment and vaccination.Revista de neurologia · 2022Article
- When is the SARS-CoV-2 infection over and what is post-COVID?Annals of medicine and surgery (2012) · 2022Article
- The diagnosis of SARS-CoV-2 associated ADEM requires the exclusion of all differential diagnoses.Annals of medicine and surgery (2012) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronavirus disease (COVID-19) usually starts with pulmonary signs and symptoms. However, in some cases, the initial clinical presentations are extrapulmonary. This literature review aimed at summarizing and discussing the extrapulmonary onset manifestations of COVID-19. The most frequent initial extrapulmonary manifestations include hypogeusia, hyposmia, non-specific abdominal symptoms, corneal congestion, and deep venous thrombosis. Several rarer extrapulmonary manifestations in locations such as the brain, peripheral nerves, muscles, eyes, ears, myocardium, intestines, skin, or vessels have been additionally reported as onset presentations of COVID-19. In conclusion, it is crucial for clinicians and health care providers to consider extrapulmonary presentations at the onset of COVID-19 to avoid overlooking the infection and contributing to the spread of the disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.