Evidence map›Paper›PMID 34231098›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2022

Incidence of new-onset atrial fibrillation in COVID-19 is associated with increased epicardial adipose tissue.

Leandro Slipczuk, Francesco Castagna, Alison Schonberger, Eitan Novogrodsky, Damini Dey, Ulrich P Jorde, Jeffrey M Levsky, Luigi Di Biase, Mario J Garcia

Open access · bronzeAbstract read
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Leandro SlipczukCardiology Division, Montefiore Medical Center, 111 E 210th, Bronx, NY, 10467, USA. lslipczukb@montefiore.org.ORCID http://orcid.org/0000-0003-3091-3735
Francesco CastagnaCardiology Division, Montefiore Medical Center, 111 E 210th, Bronx, NY, 10467, USA.
Alison SchonbergerRadiology Division, Montefiore Medical Center, Bronx, NY, USA.
Eitan NovogrodskyRadiology Division, Montefiore Medical Center, Bronx, NY, USA.
Damini DeyCedars-Sinai Medical Center, Los Angeles, CA, USA.
Ulrich P JordeCardiology Division, Montefiore Medical Center, 111 E 210th, Bronx, NY, 10467, USA.
Jeffrey M LevskyAlbert Einstein College of Medicine, Bronx, NY, USA.
Luigi Di BiaseCardiology Division, Montefiore Medical Center, 111 E 210th, Bronx, NY, 10467, USA.
Mario J GarciaCardiology Division, Montefiore Medical Center, 111 E 210th, Bronx, NY, 10467, USA.
Albert Einstein College of Medicine · USMontefiore Medical Center · USCedars-Sinai Medical Center · US

Funding

Automated quantitative CT imaging of epicardial adipose tissue and risk of cardiac eventsR01HL133616 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI DEY, DAMINI · 2016 to 2019
$2.6M
Mechanisms of cardiovascular diseaseT32HL144456 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Carlos Jose Rodriguez, Nicholas E Sibinga · 2019 to 2026
$1.9M
NHLBI NIH HHS R01 HL133616NHLBI NIH HHS R01HL133616NHLBI NIH HHS T32 HL144456
6 · The paper itself

Abstract

purposeCoronary artery calcium (CAC) and epicardial adipose tissue (EAT) can predict AF in the general population. We aimed to determine if CAC and EAT measured by computed tomographic (CT) scanning can predict new-onset AF in patients admitted with COVID-19 disease.

methodsWe performed a retrospective, post hoc analysis of all patients admitted to Montefiore Medical Center with a confirmed COVID-19 diagnosis from March 1st to June 23rd, 2020, who had a non-contrast CT of the chest within 5 years prior to admission. We determined ordinal CAC scores and quantified the EAT volume and examined their relationship with inpatient mortality.

resultsA total of 379 patients were analyzed. There were 16 events of new-onset AF (4.22%). Patients who developed AF during the index admission were more likely to be male (75 vs 47%, p < 0.001) and had higher EAT (129.5 [76.3-197.3] vs 91.0 [60.0-129.0] ml, p = 0.049). There were no differences on age (68 [56-71] vs 68 [58-76] years; p = 0.712), BMI (28.5 [25.3-30.8] vs 26.9 [23.1-31.8] kg/m

conclusionIncreased EAT measured by non-contrast chest CT identifies patients hospitalized with COVID-19 at higher risk of developing new-onset AF. Patients with new-onset AF have worse clinical outcomes.

Indexed as

Atrial FibrillationCOVID-19Adipose TissueAgedCOVID-19 TestingFemaleHumansIncidenceMaleMiddle AgedPericardiumRetrospective StudiesRisk FactorsAtrial fibrillationCoronary artery calciumCOVID-19Epicardial adipose tissue

Identifiers

PMID34231098
PMCPMC8260236
OpenAlexW3178135205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.