ArticleThe South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa2021
Associations of premorbid adjustment with type and timing of childhood trauma in first-episode schizophrenia spectrum disorders.
Article in The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Relationships between trauma types and psychotic symptoms: A network analysis of patients with psychotic disorders in a large, multi-country study in East Africa.Comprehensive psychiatry · 2024Article
- Latent Profiles of Premorbid Adjustment in Schizophrenia and Their Correlation with Measures of Recovery.Journal of clinical medicine · 2022Article
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7 authors.
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Abstract
backgroundChildhood trauma may contribute to poorer premorbid social and academic adjustment which may be a risk factor for schizophrenia.
aimWe explored the relationship between premorbid adjustment and childhood trauma, timing of childhood trauma's moderating role as well as the association of clinical and treatment-related confounders with premorbid adjustment.
settingWe conducted a secondary analysis in 111 patients with first-episode schizophrenia (FES) disorders that formed part of two parent studies, EONKCS study (
methodsType of childhood trauma was assessed with the Childhood Trauma Questionnaire, short-form and premorbid adjustment using the Premorbid Adjustment Scale. Timing of childhood trauma was assessed using the Life Events Checklist and life events timeline. Linear regression analyses were used to assess the moderating effect of timing of childhood trauma. Clinical and treatment-related confounders were entered into sequential hierarchical regression models to identify independent predictors of premorbid adjustment across key life stages.
resultsChildhood physical neglect was associated with poorer premorbid academic functioning during childhood and early adolescence, and poorer premorbid social functioning during early and late adolescence. By hierarchical regression modelling (
conclusionIn patients with FES, childhood physical neglect may contribute to poorer premorbid social functioning during early adolescence. This may provide us with an opportunity to identify and treat at-risk individuals earlier.
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