Evidence map›Paper›PMID 34230825›Full record

ArticleAdvanced functional materials2021

A HiPAD Integrated with rGO/MWCNTs Nano-Circuit Heater for Visual Point-of-Care Testing of SARS-CoV-2.

Sijie Li, Shiyi Huang, Yuqing Ke, Hongjun Chen, Jingqi Dang, Chengjie Huang, Wenjia Liu, Daxiang Cui, Jinglin Wang, Xiao Zhi and 1 more

Abstract read
In one paragraph

Article in Advanced functional materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  10. Tetrahedral DNA framework assisted rotational paper-based analytical device for differential detection of SARS-CoV-2 and influenza A H1N1 virus.Microchemical journal : devoted to the application of microtechniques in all branches of science · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sijie LiState Key Laboratory of Oncogenes and Related Genes Institute for Personalized Medicine School of Biomedical Engineering Shanghai Jiao Tong University 1954 Huashan RD, Xuhui District Shanghai 200030 China.
Shiyi HuangState Key Laboratory of Oncogenes and Related Genes Institute for Personalized Medicine School of Biomedical Engineering Shanghai Jiao Tong University 1954 Huashan RD, Xuhui District Shanghai 200030 China.
Yuqing KeState Key Laboratory of Oncogenes and Related Genes Institute for Personalized Medicine School of Biomedical Engineering Shanghai Jiao Tong University 1954 Huashan RD, Xuhui District Shanghai 200030 China.
Hongjun ChenShanghai Veterinary Research Institute 518 Ziyue Road, Minhang District Shanghai 200241 China.
Jingqi DangState Key Laboratory of Oncogenes and Related Genes Institute for Personalized Medicine School of Biomedical Engineering Shanghai Jiao Tong University 1954 Huashan RD, Xuhui District Shanghai 200030 China.
Chengjie HuangState Key Laboratory of Oncogenes and Related Genes Institute for Personalized Medicine School of Biomedical Engineering Shanghai Jiao Tong University 1954 Huashan RD, Xuhui District Shanghai 200030 China.
Wenjia LiuState Key Laboratory of Oncogenes and Related Genes Institute for Personalized Medicine School of Biomedical Engineering Shanghai Jiao Tong University 1954 Huashan RD, Xuhui District Shanghai 200030 China.
Daxiang CuiShanghai Engineering Center for Intelligent Diagnosis and Treatment Instrument School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University 800 Dongchuan RD, Minghang District Shanghai 200240 China.
Jinglin WangState Key Laboratory of Pathogen and Biosecurity Institute of Microbiology and Epidemiology 20 Dongda Street, Fengtai District Beijing 100071 China.
Xiao ZhiState Key Laboratory of Oncogenes and Related Genes Institute for Personalized Medicine School of Biomedical Engineering Shanghai Jiao Tong University 1954 Huashan RD, Xuhui District Shanghai 200030 China.
Xianting DingState Key Laboratory of Oncogenes and Related Genes Institute for Personalized Medicine School of Biomedical Engineering Shanghai Jiao Tong University 1954 Huashan RD, Xuhui District Shanghai 200030 China.ORCID https://orcid.org/0000-0002-1549-3499

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nowadays, the main obstacle for further miniaturization and integration of nucleic acids point-of-care testing devices is the lack of low-cost and high-performance heating materials for supporting reliable nucleic acids amplification. Herein, reduced graphene oxide hybridized multi-walled carbon nanotubes nano-circuit integrated into an ingenious paper-based heater is developed, which is integrated into a paper-based analytical device (named HiPAD). The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still raging across the world. As a proof of concept, the HiPAD is utilized to visually detect the SARS-CoV-2 N gene using colored loop-mediated isothermal amplification reaction. This HiPAD costing a few dollars has comparable detection performance to traditional nucleic acids amplifier costing thousands of dollars. The detection range is from 25 to 2.5 × 10

Indexed as

multi‐walled carbon nanotubespaper‐based analytical devicespoint‐of‐care testingreduced graphene oxideSARS‐CoV‐2

Identifiers

PMID34230825
PMCPMC8250055

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.