Evidence map›Paper›PMID 34230748›Full record

ArticleApplied mathematical modelling2021

Malaria and COVID-19 co-dynamics: A mathematical model and optimal control.

S Y Tchoumi, M L Diagne, H Rwezaura, J M Tchuenche

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Article in Applied mathematical modelling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

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32citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. A mathematical model for the co-dynamics of COVID-19 and tuberculosis.Mathematics and computers in simulation · 2023
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  16. Analysis of HBV and COVID-19 Coinfection Model with Intervention Strategies.Computational and mathematical methods in medicine · 2023
    Article
  17. Article
  18. Article
  19. Dynamic stability and optimal control of SISChaos, solitons, and fractals · 2022
    Article
  20. Article
4 · The record

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5 · Who and what money

Authors and funding

4 authors.

S Y TchoumiDepartment of Mathematics and Computer Sciences ENSAI, University of NGaoundere, P.O. Box 455 Ngaoundere, Cameroon.
M L DiagneDepartement de Mathematiques, UFR des Sciences et Technologies, Universite de Thies, Thies, Senegal.
H RwezauraMathematics Department, University of Dar es Salaam, P.O. Box 35062, Dar es Salaam, Tanzania.
J M TchuencheSchool of Computer Science and Applied Mathematics, University of the Witwatersrand, Private Bag 3, Wits Johannesburg, 2050, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria, one of the longest-known vector-borne diseases, poses a major health problem in tropical and subtropical regions of the world. Its complexity is currently being exacerbated by the emerging COVID-19 pandemic and the threats of its second wave and looming third wave. We formulate and analyze a mathematical model incorporating some epidemiological features of the co-dynamics of both malaria and COVID-19. Sufficient conditions for the stability of the malaria only and COVID-19 only sub-models' equilibria are derived. The COVID-19 only sub-model has globally asymptotically stable equilibria while under certain condition, the malaria-only could undergo the phenomenon of backward bifurcation whenever the sub-model reproduction number is less than unity. The equilibria of the dual malaria-COVID19 model are locally asymptotically stable as global stability is precluded owing to the possible occurrence of backward bifurcation. Optimal control of the full model to mitigate the spread of both diseases and their co-infection are derived. Pontryagin's Maximum Principle is applied to establish the existence of the optimal control problem and to derive the necessary conditions for optimal control of the diseases. Though this is not a case study, simulation results to support theoretical analysis of the optimal control suggests that concurrently applying malaria and COVID-19 protective measures could help mitigate their spread compared to applying each preventive control measure singly as the world continues to deal with this unprecedented and unparalleled COVID-19 pandemic.

Identifiers

PMID34230748
PMCPMC8249695

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.