Evidence map›Paper›PMID 34230621›Full record

SynthesisPediatric research2022

Carbon dioxide levels in neonates: what are safe parameters?

Sie Kei Wong, M Chim, J Allen, A Butler, J Tyrrell, T Hurley, M McGovern, M Omer, N Lagan, J Meehan and 2 more

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Pediatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. CAPNO study-Capnometry during neonatal transport.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  8. Observational
  9. Article
  10. Review
  11. Article
  12. Validation of a novel Bayesian predictive algorithm for detection of carbon dioxide retention using retrospective neonatal ICU data.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  13. Article
  14. Physicians' eye-tracking in neonatal intensive care: evaluating a mechanical ventilator panel.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2026
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Sie Kei WongDepartment of Paediatrics, School of Medicine, Trinity College, The University of Dublin, Trinity Translational Medicine Institute (TTMI) & Trinity Research in Childhood Centre (TRiCC), Dublin, Ireland.
M ChimDepartment of Paediatrics, School of Medicine, Trinity College, The University of Dublin, Trinity Translational Medicine Institute (TTMI) & Trinity Research in Childhood Centre (TRiCC), Dublin, Ireland.
J AllenDepartment of Paediatrics, School of Medicine, Trinity College, The University of Dublin, Trinity Translational Medicine Institute (TTMI) & Trinity Research in Childhood Centre (TRiCC), Dublin, Ireland.
A ButlerDepartment of Paediatrics, School of Medicine, Trinity College, The University of Dublin, Trinity Translational Medicine Institute (TTMI) & Trinity Research in Childhood Centre (TRiCC), Dublin, Ireland.
J TyrrellDepartment of Paediatrics, School of Medicine, Trinity College, The University of Dublin, Trinity Translational Medicine Institute (TTMI) & Trinity Research in Childhood Centre (TRiCC), Dublin, Ireland.
T HurleyDepartment of Paediatrics, School of Medicine, Trinity College, The University of Dublin, Trinity Translational Medicine Institute (TTMI) & Trinity Research in Childhood Centre (TRiCC), Dublin, Ireland.
M McGovernDepartment of Paediatrics, School of Medicine, Trinity College, The University of Dublin, Trinity Translational Medicine Institute (TTMI) & Trinity Research in Childhood Centre (TRiCC), Dublin, Ireland.
M OmerDepartment of Paediatrics, School of Medicine, Trinity College, The University of Dublin, Trinity Translational Medicine Institute (TTMI) & Trinity Research in Childhood Centre (TRiCC), Dublin, Ireland.
N LaganDepartment of Paediatrics, School of Medicine, Trinity College, The University of Dublin, Trinity Translational Medicine Institute (TTMI) & Trinity Research in Childhood Centre (TRiCC), Dublin, Ireland.
J MeehanDepartment of Paediatrics, School of Medicine, Trinity College, The University of Dublin, Trinity Translational Medicine Institute (TTMI) & Trinity Research in Childhood Centre (TRiCC), Dublin, Ireland.
E P CumminsSchool of Medicine and Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
E J MolloyDepartment of Paediatrics, School of Medicine, Trinity College, The University of Dublin, Trinity Translational Medicine Institute (TTMI) & Trinity Research in Childhood Centre (TRiCC), Dublin, Ireland. Eleanor.molloy@tcd.ie.
Trinity College Dublin · IETallaght University Hospital · IEUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is no consensus on the optimal pCO

Indexed as

HypocapniaInfant, Premature, DiseasesCarbon DioxideHumansHypercapniaInfant, NewbornInfant, PrematureRespiration, ArtificialCarbon Dioxide

Identifiers

PMID34230621
PMCPMC9122818
OpenAlexW3182275023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.