Evidence map›Paper›PMID 34230598›Full record

ArticleScientific reports2021

Innovative finding of 266-nm laser regulating CD90 levels in SDSCs.

Ray-Ling Hsiao, Yen-Chung Chen, Mei-Yue Huang, Chiang-Yun Chen, Yu-Wei Lin, Chung-Yi Wu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Ray-Ling HsiaoPh.D. Program for Cancer Biology and Drug Discovery, China Medical University and Academia Sinica, Taichung, Taiwan, ROC. rayling.hsiao@msa.hinet.net.
Yen-Chung ChenMaria Von Med-Biotechnology Co., Ltd, Taipei, Taiwan, ROC.
Mei-Yue HuangMaria Von Med-Biotechnology Co., Ltd, Taipei, Taiwan, ROC.
Chiang-Yun ChenGenomics Research Center, Academia Sinica, Taipei, Taiwan, ROC.
Yu-Wei LinGenomics Research Center, Academia Sinica, Taipei, Taiwan, ROC.
Chung-Yi WuGenomics Research Center, Academia Sinica, Taipei, Taiwan, ROC. cyiwu@gate.sinica.edu.tw.
Genomics Research Center, Academia Sinica · TWAcademia Sinica · TWDevelopment Center for Biotechnology · TWTaipei Institute of Pathology · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We used light to irradiate skin-derived stem cells and tried to find any cellular protein alterations 24 h after illumination. A 266-nm laser with four intensities was used, and of the nine cell markers that were surveyed in our trials, only CD90 was downregulated at an intensity of 20 μJ for 10 s. Repeated illuminations from the 266-nm laser at seven intensities revealed that CD90 expression was downregulated 14.6-28.8%, depending on light intensity. The maximal effect was noted at an intensity of 30 μJ for 2 s. This innovative finding reveals that a 266-nm laser can regulate protein expression in skin-derivative stem cells.

Indexed as

LasersA549 CellsBiomarkersFluorescenceHumansNucleotidesSkinStem CellsThy-1 AntigensBiomarkersNucleotidesThy-1 Antigens

Identifiers

PMID34230598
PMCPMC8260621
OpenAlexW3182942225

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.