Evidence map›Paper›PMID 34230489›Full record

ArticleScientific data2021

An automatic multi-tissue human fetal brain segmentation benchmark using the Fetal Tissue Annotation Dataset.

Kelly Payette, Priscille de Dumast, Hamza Kebiri, Ivan Ezhov, Johannes C Paetzold, Suprosanna Shit, Asim Iqbal, Romesa Khan, Raimund Kottke, Patrice Grehten and 10 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  4. Deep learning in fetal, infant, and toddler neuroimaging research.Developmental cognitive neuroscience · 2026
    Review
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  11. TMagnetic resonance in medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Kelly PayetteCenter for MR Research, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland. kelly.payette@kispi.uzh.ch.ORCID 0000-0001-7041-0150
Priscille de DumastCIBM, Center for Biomedical Imaging, Lausanne, Switzerland.ORCID 0000-0003-0359-9365
Hamza KebiriCIBM, Center for Biomedical Imaging, Lausanne, Switzerland.ORCID 0000-0001-7592-3166
Ivan EzhovImage-Based Biomedical Imaging Group, Technical University of Munich, München, Germany.
Johannes C PaetzoldImage-Based Biomedical Imaging Group, Technical University of Munich, München, Germany.
Suprosanna ShitImage-Based Biomedical Imaging Group, Technical University of Munich, München, Germany.
Asim IqbalNeuroscience Center Zurich, University of Zurich/ETH Zurich, Zurich, Switzerland.ORCID 0000-0003-2174-4554
Romesa KhanNeuroscience Center Zurich, University of Zurich/ETH Zurich, Zurich, Switzerland.
Raimund KottkeDepartment of Diagnostic Imaging, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0003-0166-2770
Patrice GrehtenDepartment of Diagnostic Imaging, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
Hui JiCenter for MR Research, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
Levente LancziFaculty of Medicine, Department of Medical Imaging, University of Debrecen, Debrecen, Hajdú-Bihar, Hungary.
Marianna NagyFaculty of Medicine, Department of Medical Imaging, University of Debrecen, Debrecen, Hajdú-Bihar, Hungary.
Monika BeresovaFaculty of Medicine, Department of Medical Imaging, University of Debrecen, Debrecen, Hajdú-Bihar, Hungary.
Thi Dao NguyenNewborn Research, Department of Neonatology, University Hospital and University of Zurich, Zurich, Switzerland.
Giancarlo NatalucciNewborn Research, Department of Neonatology, University Hospital and University of Zurich, Zurich, Switzerland.ORCID 0000-0003-0225-2431
Theofanis KarayannisBrain Research Institute, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-3267-6254
Bjoern MenzeImage-Based Biomedical Imaging Group, Technical University of Munich, München, Germany.ORCID 0000-0003-4136-5690
Meritxell Bach CuadraCIBM, Center for Biomedical Imaging, Lausanne, Switzerland.ORCID 0000-0003-2730-4285
Andras JakabCenter for MR Research, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 205321-182602
6 · The paper itself

Abstract

It is critical to quantitatively analyse the developing human fetal brain in order to fully understand neurodevelopment in both normal fetuses and those with congenital disorders. To facilitate this analysis, automatic multi-tissue fetal brain segmentation algorithms are needed, which in turn requires open datasets of segmented fetal brains. Here we introduce a publicly available dataset of 50 manually segmented pathological and non-pathological fetal magnetic resonance brain volume reconstructions across a range of gestational ages (20 to 33 weeks) into 7 different tissue categories (external cerebrospinal fluid, grey matter, white matter, ventricles, cerebellum, deep grey matter, brainstem/spinal cord). In addition, we quantitatively evaluate the accuracy of several automatic multi-tissue segmentation algorithms of the developing human fetal brain. Four research groups participated, submitting a total of 10 algorithms, demonstrating the benefits the dataset for the development of automatic algorithms.

Indexed as

FetusNeurogenesisAlgorithmsBenchmarkingBrainCongenital AbnormalitiesData CurationHumansMagnetic Resonance ImagingOrgan Size

Identifiers

PMID34230489
PMCPMC8260784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.