ArticleNature communications2021
Neofunctionalisation of the Sli gene leads to self-compatibility and facilitates precision breeding in potato.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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46 citing papers in PubMed, 85 citations in OpenAlex.
- Engineering potato inbred lines expressing Cry1Ac and Cry3A for dual resistance to potato tuber moth and Colorado potato beetle.aBIOTECH · 2026Article
- Molecular Targets and Trait Innovation in CRISPR-Edited Vegetable Crops: An Up-to-Date Review (2020-2026).Plants (Basel, Switzerland) · 2026Review
- Genome Editing in Solanaceae: Harnessing CRISPR-Cas Technology for Precision Crop Improvement.Plants (Basel, Switzerland) · 2026Review
- Unraveling the Intertwined Networks of Potato Tuberization: From Epitranscriptomic Signaling to Metabolic Reprogramming.International journal of molecular sciences · 2026Review
- Generating self-incompatible hybrid potatoes through haploid breeding.Nature plants · 2026Article
- Breaking self-incompatibility for diploid hybrid potato breeding: advances, mechanisms, and emerging technologies.Frontiers in plant science · 2026Review
- Inbreeding depression in diploid potato: genetic basis, deleterious load, and breeding mitigation.Frontiers in plant science · 2026Review
- Creating inbred lines for heterosis utilization in alfalfa.Science China. Life sciences · 2026Article
- Pan-S-locus analysis reveals insights into the origin and evolution of self-incompatibility in the orange subfamily.Genome biology · 2025Article
- CRISPR-Cas Gene Editing Technology in Potato.International journal of molecular sciences · 2025Review
- Molecular mechanisms and genetic regulation of self-incompatibility in flowering plants: implications for crop improvement and evolutionary biology.Plant molecular biology · 2025Review
- Origin of a self-compatibility associated MITE in Petota and its application in hybrid potato breeding.The New phytologist · 2025Article
- Jan and mini-Jan, a model system for potato functional genomics.Plant biotechnology journal · 2025Article
- SpudDB: a database for accessing potato genomic data.Genetics · 2025Article
- Evolution of agricultural biotechnology is the paradigm shift in crop resilience and development: a review.Frontiers in plant science · 2025Review
- The Quest for thePotato research · 2025Article
- Jan and mini-Jan, a model system for potato functional genomics.bioRxiv : the preprint server for biology · 2024Article
- Diploid inbred-based hybrids: fast-forward breeding approach in potatoes.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
- Application of genome editing in plant reproductive biology: recent advances and challenges.Plant reproduction · 2024Review
- Integrative multi-omics analysis reveals genetic and heterotic contributions to male fertility and yield in potato.Nature communications · 2024Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic gain in potato is hampered by the heterozygous tetraploid genome of cultivated potato. Converting potato into a diploid inbred-line based F1-hybrid crop provides a promising route towards increased genetic gain. The introduction of a dominant S-locus inhibitor (Sli) gene into diploid potato germplasm allows efficient generation of self-fertilized seeds and thus the development of potato inbred lines. Little is known about the structure and function of the Sli locus. Here we describe the mapping of Sli to a 12.6 kb interval on chromosome 12 using a recombinant screen approach. One of two candidate genes present in this interval shows a unique sequence that is exclusively present in self-compatible lines. We describe an expression vector that converts self-incompatible genotypes into self-compatible and a CRISPR-Cas9 vector that converts SC genotypes into SI. The Sli gene encodes an F-box protein that is specifically expressed in pollen from self-compatible plants. A 533 bp insertion in the promotor of that gene leads to a gain of function mutation, which overcomes self-pollen rejection.
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