ArticleNature communications2021
Large-scale characterization of sex pheromone communication systems in Drosophila.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed.
- Mating imperatives drive plasticity of the daily temporal niche in fruit flies.Nature ecology & evolution · 2026Article
- Fruit odors enhance attractiveness of maleiScience · 2026Article
- Modular Sensory and Morphological Adaptations Underlying Fresh-Fruit Exploitation in Drosophilid Flies.Biology · 2026Article
- Cryo-EM structures of Drosophila OR67d-Orco complexes reveal insect pheromone sensing mechanism.Cell research · 2026Article
- Cross-Species Social Experience Suppresses Aggression in Drosophila.Neuroscience bulletin · 2026Article
- Germline and male somatic determinants of sperm length divergence in Drosophila: implications for postcopulatory sexual selection.Genetics · 2026Article
- Advances and Prospects in Odour-based Management of Filth Flies.Journal of chemical ecology · 2026Review
- Evolutionary basis of male same-sex sexual behavior by multiple pheromone switches in Drosophila.Current biology : CB · 2026Article
- Rapid Genomic Adaptation of Drosophila Melanogaster to Wolbachia Elimination.Microbial ecology · 2026Article
- Strain variation identifies a neural substrate for behavioral evolution in Drosophila.Current biology : CB · 2026Article
- Genetic Basis of Cuticular Hydrocarbon Variation in the Desert AntEcology and evolution · 2026Article
- Cyclohexyl acetate functions like a volatile sex pheromone mimic in Caenorhabditis nematodes.BMC biology · 2026Article
- Insect Lipidomics: Advances, Applications, and Physiological Insights.Advances in experimental medicine and biology · 2026Review
- Neural evolution of complex motor behaviors: insights from Drosophila courtship song.Current opinion in neurobiology · 2025Review
- From neurons to novelty: Circuit mechanisms shaping courtship evolution.Current opinion in neurobiology · 2025Review
- Evolutionary basis of intermale sexual behavior by multiple pheromone switches inbioRxiv : the preprint server for biology · 2025Article
- Ecological cues orchestrate concerted courtship in abioRxiv : the preprint server for biology · 2025Article
- Strain variation identifies a neural substrate for behavioral evolution inbioRxiv : the preprint server for biology · 2025Article
- Gustatory receptors interact with the serotonin pathway to regulate silkmoth stereotyped courtship behavior.BMC biology · 2025Article
- High-resolution comparative single-cell transcriptomics ofbioRxiv : the preprint server for biology · 2025Article
1 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insects use sex pheromones as a reproductive isolating mechanism to attract conspecifics and repel heterospecifics. Despite the profound knowledge of sex pheromones, little is known about the coevolutionary mechanisms and constraints on their production and detection. Using whole-genome sequences to infer the kinship among 99 drosophilids, we investigate how phylogenetic and chemical traits have interacted at a wide evolutionary timescale. Through a series of chemical syntheses and electrophysiological recordings, we identify 52 sex-specific compounds, many of which are detected via olfaction. Behavioral analyses reveal that many of the 43 male-specific compounds are transferred to the female during copulation and mediate female receptivity and/or male courtship inhibition. Measurement of phylogenetic signals demonstrates that sex pheromones and their cognate olfactory channels evolve rapidly and independently over evolutionary time to guarantee efficient intra- and inter-specific communication systems. Our results show how sexual isolation barriers between species can be reinforced by species-specific olfactory signals.
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