ArticleNeurosciences (Riyadh, Saudi Arabia)2021
Clinical and biochemical profile of Guillain Barré Syndrome in Pakistan.
Article in Neurosciences (Riyadh, Saudi Arabia), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.
- Time- and threshold-dependent cerebrospinal fluid protein elevation and albuminocytologic dissociation in Guillain-Barré syndrome: a systematic review and meta-analysis.Journal of neurology · 2026Pooled it
- The Peculiarity of Infection and Immunity Correlated with Guillain-Barré Syndrome in the HIV-Infected Population.Journal of clinical medicine · 2023Article
- Relationship between cerebrospinal fluid protein level and electrophysiologic abnormalities in the acute inflammatory demyelinating polyradiculoneuropathy variant of Guillain-Barré syndrome.German medical science : GMS e-journal · 2021Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
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Abstract
objectivesTo evaluate the frequency, distribution, characteristics, and biochemical features of Guillain-Barré syndrome (GBS).
methodsThis retrospective, case-control study was conducted between November 2018 and February 2020 at PIMS Hospital, Islamabad and Arid Agriculture University, Rawalpindi, Pakistan. The GBS patients were diagnosed through physical examination and nerve conduction study (NCS). Hemoglobin (Hb), liver function tests, renal function tests, lipid profile, and interleukin-17 levels were investigated through the blood. Cerebrospinal fluid analysis (CSF) was performed to measure albuminocytological dissociation (ACD).
resultsOne hundred and ten patients and 130 controls participated in this study. Fifty-nine (53.63 %) patients had gastrointestinal infection while 52 (47.27 %) had AIDP. IL-17 serum levels were associated with GBS showing elevated values 18.49 pg/mL (SD=4.10) in cases as compared to controls 10.66 (SD=2.09),
conclusionThe results of the current study suggest that IL-17 levels trigger autoimmunity in GBS patients. The ACD could be used as a diagnostic marker of GBS along with NCS. Antecedent infections were common in a majority of GBS patients.
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