Evidence map›Paper›PMID 34230070›Full record

ReviewJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

A Clinical Challenge: Endocrine and Imaging Investigations of Adrenal Masses.

Anders Sundin, Elif Hindié, Anca M Avram, Antoine Tabarin, Karel Pacak, David Taïeb

Abstract readReview
In one paragraph

Review in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  5. Cushing syndrome in paediatric population: who and how to screen.Journal of endocrinological investigation · 2025
    Review
  6. Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anders SundinSection of Radiology & Molecular Imaging, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Elif HindiéDepartment of Nuclear Medicine, University Hospital of Bordeaux, Bordeaux, France.
Anca M AvramDepartment of Radiology, University of Michigan, Ann Arbor, Michigan.
Antoine TabarinDepartment of Endocrinology, University Hospital of Bordeaux, Bordeaux, France.
Karel PacakSection on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD), National Institutes of Health, Bethesda, Maryland; and.
David TaïebDepartment of Nuclear Medicine, La Timone University Hospital, CERIMED, Aix-Marseille University, France david.taieb@ap-hm.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Incidentalomas are reported in 3%-4% of patients who undergo abdominal anatomic imaging, making adrenal mass evaluation a common occurrence. An adrenal mass can be caused by a variety of pathologies, such as benign cortical and medullary tumors, malignant tumors (primary or secondary), cysts, hyperplasia, hemorrhage, or more rarely infection/inflammation processes. Functioning tumors usually have increased hormonal production but they are less common. Regardless of their functional status, some tumors have the potential to behave aggressively. Anatomic and functional imaging together with biologic evaluation play a vital role in adrenal pathology subtyping. Most patients are initially evaluated by CT or MRI, which allows for tumor characterization (to a certain extent) and can rule out malignant behavior based on the absence of tumor growth during longitudinal follow-up. In the remaining patients for whom CT or MRI fail to characterize the pathogenesis of adrenal tumors, the use of specialized molecular imaging techniques should be performed after hormonal screening. This review emphasizes well-established and emerging nuclear medicine imaging modalities and describes their use across various clinical scenarios.

Indexed as

Adrenal Gland NeoplasmsDiagnostic ImagingHumans18F-FDGadrenaladrenocortical carcinomaCTincidentalomaPET/CT

Identifiers

PMID34230070
PMCPMC12530502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.