Evidence map›Paper›PMID 34229751›Full record

ArticleBiomarker research2021

Inflammation-related genes S100s, RNASE3, and CYBB and risk of leukemic transformation in patients with myelodysplastic syndrome with myelofibrosis.

Minghua Hong, Junqing Wu, Lifeng Ma, Xiaoping Han, Ting Lu, Zhaoming Wang, Jing Zhao, Lizhen Liu, Huarui Fu, Weijia Huang and 9 more

Open access · goldAbstract readLetter
In one paragraph

Article in Biomarker research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Minghua Hong *Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China.
Junqing Wu *Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China.
Lifeng MaCenter for Stem Cell and Regenerative Medicine, Stem Cell Institute, School of Medicine, Zhejiang University, 310058, Hangzhou, China.
Xiaoping HanCenter for Stem Cell and Regenerative Medicine, Stem Cell Institute, School of Medicine, Zhejiang University, 310058, Hangzhou, China.
Ting LuBone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China.
Zhaoming WangPathology Department, the First Affiliated Hospital, School of Medicine, Zhejiang University, 310003, Hangzhou, China.
Jing ZhaoPathology Department, the First Affiliated Hospital, School of Medicine, Zhejiang University, 310003, Hangzhou, China.
Lizhen LiuBone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China.
Huarui FuBone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China.
Weijia HuangBone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China.
Weiyan ZhengBone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China.
Jingsong HeBone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China.
Guoqing WeiBone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China.
Huanping WangBone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China.
Zhimei ChenBone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China.
He HuangBone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China.
Zhen CaiBone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China.
Guoji Guo *Center for Stem Cell and Regenerative Medicine, Stem Cell Institute, School of Medicine, Zhejiang University, 310058, Hangzhou, China.
Jie Sun *Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine; Institute of Hematology, Zhejiang University; Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy; Liangzhu Laboratory, Zhejiang University Medical Center, 1369 West Wenyi Road, 310003, Hangzhou, China. jsun1492@zju.edu.cn.
Zhejiang University · CNFirst Affiliated Hospital Zhejiang University · CN

Funding

National Natural Science Foundation of China 82070200Natural Science Foundation of Zhejiang Province (CN) LQ20H160025
6 · The paper itself

Abstract

Myelodysplastic syndrome with myelofibrosis (MDS-MF) has been associated with an inferior prognosis compared with MDS without MF. However, MDS-MF is not listed independently as a subtype of MDS, and its clinical and genetic characteristics remain poorly understood. We retrospectively compared 53 patients with MDS-MF (44 MF grade 1/MF

Indexed as

InflammationLeukemic transformationMyelodysplastic syndromeMyelofibrosisSingle-cell sequence

Identifiers

PMID34229751
PMCPMC8259211
OpenAlexW3177951316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.