Evidence map›Paper›PMID 34229622›Full record

ArticleBMC nephrology2021

Renal transplantation after recovery from COVID-19 - a case report with implications for transplant programs in the face of the ongoing corona-pandemic.

Katharina Tuschen, Johanna Anders, Amin Elfanish, Verena Schildgen, Oliver Schildgen, Jan Ulrich Becker, Alexander Weidemann

Abstract readCase Reports
In one paragraph

Article in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katharina TuschenMedizinische Klinik III, Nephrologie und Dialyse, St. Vincenz-Krankenhaus Paderborn, Am Busdorf 2, 33098, Paderborn, Germany.
Johanna AndersMedizinische Klinik I, Nephrologie, Transplantation und Internistische Intensivmedizin, Krankenhaus Merheim, Kliniken der Stadt Köln, Klinikum der Universität Witten/Herdecke, Köln, Germany.
Amin ElfanishMedizinische Klinik I, Nephrologie, Transplantation und Internistische Intensivmedizin, Krankenhaus Merheim, Kliniken der Stadt Köln, Klinikum der Universität Witten/Herdecke, Köln, Germany.
Verena SchildgenInstitut für Pathologie der Kliniken der Stadt Köln, Klinikum der Universität Witten/Herdecke, Köln, Germany.
Oliver SchildgenInstitut für Pathologie der Kliniken der Stadt Köln, Klinikum der Universität Witten/Herdecke, Köln, Germany.
Jan Ulrich BeckerInstitut für Pathologie, Uniklinik Köln, Köln, Germany.
Alexander WeidemannMedizinische Klinik III, Nephrologie und Dialyse, St. Vincenz-Krankenhaus Paderborn, Am Busdorf 2, 33098, Paderborn, Germany. a.weidemann@vincenz.de.ORCID 0000-0002-7984-9597

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ongoing coronavirus pandemic has major impacts on both patients and healthcare systems worldwide, thus creating new realities. Patients on maintenance dialysis listed for renal transplantation are a vulnerable subgroup with many comorbidities and recurring contacts with the healthcare system. Due to the COVID-19 pandemic transplant numbers have dropped considerably, further increasing waiting times in this high-risk population. On the other hand, knowledge of the severity of SARS-CoV-2 infection in immunocompromised patients, development and persistence of neutralising antibodies in such patients is just emerging. It is unclear how best to address the dilemma of postponing the life-saving transplantation. CASE PRESENTATION: We present a case report of a successful kidney transplantation only 65 days after the recipient was hospitalized for treatment of COVID-19 pneumonia. In a follow up of 9 months, we observed no signs of recurrent disease and transplant function is excellent. Monitoring SARS-CoV-2 antibody response demonstrates stable IgG levels.

conclusionThis reassuring case provides guidance to transplant centers how to proceed with kidney transplantation safely during the pandemic. Careful consideration of risks and benefits of the organ offer, full recovery from COVID-19 symptoms and the presence of a positive SARS-CoV-2 IgG antibody test, qualifies for kidney transplantation.

Indexed as

Kidney TransplantationAgedAntibodies, ViralCOVID-19COVID-19 Serological TestingFemaleGraft RejectionHumansImmunoglobulin GImmunoglobulin MImmunosuppressive AgentsKidney Failure, ChronicRenal DialysisSARS-CoV-2Antibodies, ViralImmunoglobulin GImmunoglobulin MImmunosuppressive AgentsAntibody responseImmunosuppressionKidney transplantationReactivationSARS-CoV-2

Identifiers

PMID34229622
PMCPMC8258483

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.