Evidence map›Paper›PMID 34229543›Full record

ReviewCell cycle (Georgetown, Tex.)2021

The emerging role of miR-10 family in gastric cancer.

Fang Liu, Yanfen Shi, Zuolong Liu, Ziyi Li, Wei Xu

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell cycle (Georgetown, Tex.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Fang LiuDepartment of Emergency, The First Hospital of Jilin University, Changchun, Jilin, China.
Yanfen ShiDepartment of Pathology, China-Japan Friendship Hospital, Beijing, China.
Zuolong LiuDepartment of Emergency, The First Hospital of Jilin University, Changchun, Jilin, China.
Ziyi LiKey Laboratory of Organ Regeneration and Transplantation of Ministry of Education, The First Hospital of Jilin University, Changchun, Jilin, China.ORCID 0000-0001-8815-5696
Wei XuDepartment of the Clinical Laboratory, The First Hospital of Jilin University, Changchun, Jilin, China.
Jilin University · CNChina-Japan Friendship Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence has demonstrated that miRNAs play an irreplaceable role in tumorigenesis and progression of a broad range of cancers, including gastric cancer. Among these miRNAs, miR-10a and miR-10b have been identified to critically participate in gastric carcinogenesis and malignant progression. In this review, we briefly describe the role of miR-10a and miR-10b in gastric cancer, especially in the regulation of cell proliferation, apoptosis, cell cycle, migration, invasion and metastasis, drug resistance, and cancer stem cells. Furthermore, we highlight several compounds that target the miR-10 family and exhibit antitumor activity in cancer cells. Moreover, we conclude that targeting the miR-10 family might be a promising approach for the treatment of gastric cancer.

Indexed as

AnimalsAntineoplastic AgentsApoptosisCell CycleCell MovementCell ProliferationDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticHumansMembrane GlycoproteinsNeoplasm InvasivenessNeoplastic Stem CellsReceptors, ImmunologicSignal TransductionStomach NeoplasmsAntineoplastic AgentsLILRB2 protein, humanMembrane GlycoproteinsReceptors, ImmunologicGastric cancerinvasionmiR-10proliferationtreatment

Identifiers

PMID34229543
PMCPMC8354661
OpenAlexW3183111398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.