ArticleAmerican journal of physiology. Renal physiology2021
L-WNK1 is required for BK channel activation in intercalated cells.
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Article in American journal of physiology. Renal physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- The evolving concepts of KS-WNK1 effect on NCC activity.American journal of physiology. Renal physiology · 2025Review
- Familial Hyperkalemic Hypertension.Comprehensive Physiology · 2024Review
- Aldosterone-independent regulation of K + secretion in the distal nephron.Current opinion in nephrology and hypertension · 2024Review
- Cannabinoid receptor type 1 activation causes a water diuresis by inducing an acute central diabetes insipidus in mice.American journal of physiology. Renal physiology · 2024Article
- Circadian Rhythm Regulation by Pacemaker Neuron Chloride Oscillation in Flies.Physiology (Bethesda, Md.) · 2024Review
- Epithelial NaComprehensive Physiology · 2024Review
- PIEZO1 is a distal nephron mechanosensor and is required for flow-induced K+ secretion.The Journal of clinical investigation · 2024Article
- Tubular deficiency of ABCA1 augments cholesterol- and NaAmerican journal of physiology. Renal physiology · 2024Article
- Navigating the kidney organoid: insights into assessment and enhancement of nephron function.American journal of physiology. Renal physiology · 2023Review
- Pendrin regulation is prioritized by anion in high-potassium diets.American journal of physiology. Renal physiology · 2023Article
- WNK1 is a chloride-stimulated scaffold that regulates mTORC2 activity and ion transport.Journal of cell science · 2022Article
- Physiology assays in human kidney organoids.American journal of physiology. Renal physiology · 2022Review
- Chloride oscillation in pacemaker neurons regulates circadian rhythms through a chloride-sensing WNK kinase signaling cascade.Current biology : CB · 2022Article
- Salt sensitivity of volume and blood pressure in a mouse with globally reduced ENaC γ-subunit expression.American journal of physiology. Renal physiology · 2021Article
Corrections and comments
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Authors and funding
16 authors at 4 institutions in 1 country.
Evan C RayDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0003-1491-4869
Rolando Carrisoza-GaytanDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.
Mohammad Al-BatainehDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0001-9521-480X
Allison L MarciszynDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Lubika J NkashamaDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Jingxin ChenDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Aaliyah WinfreyDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Shawn GriffithsDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Tracey R LamDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Daniel FloresDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.
Peng WuDepartment of Pharmacology, New York Medical College, Valhalla, New York.
WenHui WangDepartment of Pharmacology, New York Medical College, Valhalla, New York.
Chou-Long HuangDepartment of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa.
Arohan R SubramanyaDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0002-2609-7643
Thomas R KleymanDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0002-2413-5415
Lisa M SatlinDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.
University of Pittsburgh · USIcahn School of Medicine at Mount Sinai · USNew York Medical College · USUniversity of Iowa · US
Funding
Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2008 to 2022
$13.4MRegulation of K and H secretion by intercalated cellsR01DK038470 · NIDDK · YESHIVA UNIVERSITY · PI HUGHEY, REBECCA P, KLEYMAN, THOMAS R · 1994 to 2022
$7.7MRole of Kir4.1 in Regulating NCC and ROMK in DCTR01DK054983 · NIDDK · NEW YORK MEDICAL COLLEGE · PI ELLISON, DAVID H, WANG, WENHUI · 2001 to 2020
$7.4MENaC regulation and its role in blood pressure homeostasisR01HL147818 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Annet Kirabo, Thomas R Kleyman · 2019 to 2026
$4.6MControl of the Renal WNK Signaling Pathway by Phase TransitionsR01DK098145 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AYLIN RACHEL RODAN, AROHAN R SUBRAMANYA · 2014 to 2026
$4.2MWNK kinase cascade in health and diseaseR01DK111542 · NIDDK · UNIVERSITY OF IOWA · PI Chou-Long Huang · 2017 to 2026
$3.6MRegulation of Renal WNK Signaling in Intercalated CellsR01DK119252 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SUBRAMANYA, AROHAN R · 2019 to 2023
$2.0MProteolytic activation of ENaC in Proteinuric Kidney DiseaseK08DK110332 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RAY, EVAN CROSS · 2016 to 2021
$903kRole of Muc1 in the b-catenin Response to Acute Kidney InjuryK01DK109038 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AL-BATAINEH, MOHAMMAD · 2016 to 2021
$798kRole of the MUC1/HIF-1a Complex in the kidney proximal tubule during ischemia-reperfusion injury.R03DK131093 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AL-BATAINEH, MOHAMMAD · 2022 to 2023
$236kRole of Kir4.1 in Regulating NCC and ROMK in DCTR56DK054983 · NIDDK · NEW YORK MEDICAL COLLEGE · PI ELLISON, DAVID H, WANG, WENHUI · 2021 to 2021
$100kRENAL INTERCALATED CELL REGULATION AND DIFFERENTIATIONR29DK038470 · NIDDK · YESHIVA UNIVERSITY · PI SATLIN, LISA M. · 1986 to 1990
–NHLBI NIH HHS R01 HL147818NIDDK NIH HHS K01 DK109038NIDDK NIH HHS K08 DK110332NIDDK NIH HHS P30 DK079307NIDDK NIH HHS R01 DK038470NIDDK NIH HHS R01 DK054983NIDDK NIH HHS R01 DK098145NIDDK NIH HHS R01 DK111542NIDDK NIH HHS R01 DK119252NIDDK NIH HHS R03 DK131093NIDDK NIH HHS R56 DK054983
Abstract
Large-conductance K
Indexed as
AnimalsIon TransportKidneyLarge-Conductance Calcium-Activated Potassium ChannelsMiceNephronsPotassiumWNK Lysine-Deficient Protein Kinase 1Large-Conductance Calcium-Activated Potassium ChannelsPotassiumWnk1 protein, mouseWNK Lysine-Deficient Protein Kinase 1intercalated cellslarge-conductance potassium channelpotassium secretionWNK1 kinase
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.