Evidence map›Paper›PMID 34229286›Full record

ArticleJournal of affective disorders2021

Comorbid alcohol-related problems and suicidality disproportionately impact men and emerging adults among individuals with depressive symptoms.

Lourah M Kelly, Richard T Liu, Kristyn Zajac

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  6. Interactive effect of adverse child experiences and suicidal thoughts and behaviors on adolescent alcohol and cannabis use frequency.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2023
    Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lourah M KellyUniversity of Connecticut School of Medicine, Farmington, CT, United States.
Richard T LiuMassachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Harvard Medical School, Boston, MA, United States.
Kristyn ZajacUniversity of Connecticut School of Medicine, Farmington, CT, United States. Electronic address: zajac@uchc.edu.
University of Connecticut · USHarvard University · US

Funding

Pilot StudiesP50AA027055 · NIAAA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI HOLZHAUER, CATHRYN GLANTON, STEFFENS, DAVID C. · 2019 to 2023
$7.8M
POST-DOCTORAL TRAINING PROGRAM IN ALCOHOL STUDIEST32AA007290 · NIAAA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI SHEILA MARIE ALESSI · 1985 to 2026
$3.2M
Neurocognitive characteristics of short-term risk for suicidal behavior in adolescents R01MH115905 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI LIU, RICHARD T · 2018 to 2023
$3.2M
Temporal dynamics of stress, sleep, and arousal in short-term risk for adolescentsuicidal behaviorRF1MH120830 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI LIU, RICHARD T · 2019 to 2019
$3.1M
A Reinforcement Intervention for Increasing HIV Testing Among At-Risk WomenR01MD013550 · NIMHD · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI ZAJAC, KRISTYN · 2018 to 2022
$2.8M
Life Stressors, Impulsivity, and Adolescent Suicidal BehaviorR01MH101138 · NIMH · EMMA PENDLETON BRADLEY HOSPITAL · PI LIU, RICHARD T · 2014 to 2018
$2.0M
Treating Co-Occurring PTSD and Substance Abuse in High-Risk Transition Age YouthK23DA034879 · NIDA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI ZAJAC, KRISTYN · 2014 to 2018
$964k
NIAAA NIH HHS L30 AA029582NIAAA NIH HHS P50 AA027055NIAAA NIH HHS T32 AA007290NIDA NIH HHS K23 DA034879NIMHD NIH HHS R01 MD013550NIMH NIH HHS R01 MH101138NIMH NIH HHS R01 MH115905NIMH NIH HHS RF1 MH120830
6 · The paper itself

Abstract

objectiveDepressive disorders are common among adults with alcohol use disorder and with suicidality; however, demographic differences in comorbid alcohol use disorder, binge drinking, and suicidality are understudied. The objective of this study was to determine the extent to which comorbid suicidality and alcohol use disorders and comorbid suicidality and binge drinking differ by age and gender among adults with depressive symptoms.

methodThe sample included adults (unweighted N=29,460) in the United States who completed the 2015-2018 National Survey of Drug Use and Heath and screened positively for depression. Gender and age groups odds of alcohol use disorder only, suicidality only, and alcohol use disorder+suicidality were compared to neither problem. Similar analyses were conducted for binge drinking.

resultsMen showed disproportional odds of alcohol use disorder only, all suicidality and alcohol use disorder comorbidities, and binge drinking+active suicidal ideation than women. Emerging adults showed higher odds of: passive and active suicidal ideation only and suicidality+alcohol use disorder than adults 35 and older; binge drinking only, binge drinking+passive suicidal ideation, and binge drinking+active suicidal ideation than all older adults; binge drinking+suicide planning and binge drinking+attempts than adults 50 and older. LIMITATIONS: Because participants all reported depression symptoms either at the subclinical or clinical level, demographic differences in suicidality, alcohol use disorder, and binge drinking found in this study cannot be generalized to non-depressed samples.

conclusionsTreatment providers should be aware of disproportionately higher odds of comorbid suicidality and alcohol use disorder, and suicidality and binge drinking among men and emerging adults.

Indexed as

AlcoholismSuicideAgedComorbidityDepressionFemaleHumansMaleSuicidal IdeationUnited StatesAlcohol use disordersBinge drinkingDepressive symptomsEmerging adultsGenderSuicidality

Identifiers

PMID34229286
PMCPMC8352104
OpenAlexW3173153788

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.