ArticleJournal of diabetes investigation2022
Lower handgrip strength levels probably precede triglyceride glucose index and associated with diabetes in men not in women.
Article in Journal of diabetes investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Clinical importance of simple muscular fitness tests to predict long-term health conditions: a systematic review and meta-analysis of 94 cohort studies.British journal of sports medicine · 2026Pooled it
- Eight weeks of aerobic exercise, but not four, improves insulin sensitivity and cardiovascular performance in young women.Scientific reports · 2025Trial
- Triglyceride-related metabolic indices and low relative muscle mass: a cross-sectional analysis of SMILE and NHANES.Endocrine · 2026Article
- Relationship between triglyceride-glucose index and muscle strength in middle-aged and older Chinese adults without chronic diseases: a nationwide longitudinal cohort study.Scientific reports · 2026Article
- Prospective association between the triglyceride-glucose index and frailty in middle-aged and older adults: insights from a nationwide cohort study.European journal of medical research · 2026Article
- Association of triglyceride-glucose related indices with cardiovascular diseases in individuals with low handgrip strength: a prospective cohort study of UK biobank.BMC cardiovascular disorders · 2026Article
- Sex- and Age-Stratified relative handgrip strength and risk of eight chronic diseases in Middle-Aged and older adults: evidence from a National aging cohort study in China.Aging clinical and experimental research · 2025Article
- N-Lactoyl amino acids as metabolic biomarkers differentiating low and high exercise response.Biology of sport · 2025Article
- Cross-sectional and longitudinal associations between glycaemic measures and grip strength in people without diabetes in the UK Biobank cohort study.European geriatric medicine · 2025Article
- Association between non-insulin-based insulin resistance indicators and frailty progression: a national cohort study and mendelian randomization analysis.Cardiovascular diabetology · 2025Article
- Association of triglyceride-glucose index and its related parameters with functional disability: evidence from the China Health and Retirement Longitudinal Study.Frontiers in aging neuroscience · 2025Article
- Investigation of the association between the triglyceride-glucose index and the incidence of frailty among middle-aged and older adults: evidence from the China health and retirement longitudinal study.Frontiers in public health · 2025Article
- Association of the triglyceride-glucose index and its related parameters with frailty.Lipids in health and disease · 2024Article
- Cross-sectional comparison of the association between three different insulin resistance surrogates and frailty: NHANES 1999-2018.Frontiers in endocrinology · 2024Article
- Biological ageing and the risk of decreased handgrip strength among community-dwelling older adult Indians: a cross-sectional study.BMC geriatrics · 2023Article
- Association of triglyceride-glucose index trajectory and frailty in urban older residents: evidence from the 10-year follow-up in a cohort study.Cardiovascular diabetology · 2023Article
- Low relative hand grip strength is associated with a higher risk for diabetes and impaired fasting glucose among the Korean population.PloS one · 2022Article
- Lower handgrip strength levels probably precede triglyceride glucose index and associated with diabetes in men not in women.Journal of diabetes investigation · 2022Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AIMS/
introductionTo explore the relationship between handgrip strength per weight (HGS/W), triglyceride glucose index (TyG) and diabetes, and whether lower HGS levels precede TyG in the Chinese elderly population. MATERIALS AND
methodsTwo linear regression models were used to explore the association of whether baseline HGS/W predicted follow-up variation of TyG or baseline TyG predicted follow-up variation of HGS/W. The logistic regression model was used to examine the relationship between baseline HGS/W and future diabetes.
resultsA total of 4,561 participants in the China Health and Retirement Longitudinal Study were enrolled, of which 47.0% were men, and the mean age was 58.7 years (standard deviation 8.68 years). A lower baseline HGS/W significantly correlated with a higher level of follow-up TyG (β = -0.173, P = 0.002). The baseline level of HGS/W was significantly negatively associated with the incidence risk of diabetes (rate ratio 0.375, P = 0.004). However, in sex stratification, the statistical association between HGS/W and TyG and diabetes was only in men.
conclusionsOur results showed that HGS/W was inversely associated with TyG and diabetes, and lower HGS/W levels preceded TyG levels in the elderly population. However, the effect was inconsistent between men and women, and the possible mechanism would require further clarification.
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