SynthesisPloS one2021
Prevalence of uterine rupture among women with one prior low transverse cesarean and women with unscarred uterus undergoing labor induction with PGE2: A systematic review and meta-analysis.
Synthesis in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Success rates of trial of labor after cesarean delivery: the impact of prior vaginal deliveries on outcomes.Archives of gynecology and obstetrics · 2026Article
- Second-Trimester Uterine Rupture in an Unscarred Uterus Following Self-Administered Misoprostol: A Case Report and Literature Review.Clinical medicine insights. Case reports · 2026Article
- Spontaneous non-laboring uterine rupture of an unscarred uterus in a 44-year-old female patient lacking predisposing factors: a case report.Journal of medical case reports · 2025Article
- Article
- Toward human uterus tissue engineering: Uterine decellularization in a non-human primate species.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Article
- Conservative management of complete fetal expulsion into the abdominal cavity after silent uterine rupture - case report.BMC pregnancy and childbirth · 2023Article
- Incidental Finding of a Broad Ligament Hematoma During Tubal Ligation Surgery: A Case Report and Literature Review.Cureus · 2023Article
- Successful vaginal delivery and maternal and perinatal outcomes in patients with a history of cesarean section and labor trial: cross-sectional studyRevista colombiana de obstetricia y ginecologia · 2022Article
- Precipitous delivery complicated by uterine artery laceration and uterine rupture in an unscarred uterus: A case report.Case reports in women's health · 2022Article
- Mechanical Methods for the Induction of Labour After Previous Caesarean Section - An Updated, Evidence-based Review.Geburtshilfe und Frauenheilkunde · 2022Article
- Use of Vaginal Dinoprostone (PGEJournal of clinical medicine · 2022Article
- Spontaneous Rupture of Unscarred Uterus in a Term Primagravida with Lethal Skeletal Dysplasia Fetus (Thanatophoric dysplasia). A Case Report and Review of the Literature.International medical case reports journal · 2022Article
- Induction of Labor with Vaginal Dinoprostone (PGEJournal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs uterine rupture may affect as many as 11/1000 women with 1 prior cesarean birth and 5/10.000 women with unscarred uterus undergoing labor induction, we intended to estimate the prevalence of such rare outcome when PGE2 is used for cervical ripening and labor induction.
methodsWe searched MEDLINE, ClinicalTrials.gov and the Cochrane library up to September 1st 2020. Retrospective and prospective cohort studies, as well as randomized controlled trials (RCTs) on singleton viable pregnancies receiving PGE2 for cervical ripening and labor induction were reviewed. Prevalence of uterine rupture was meta-analyzed with Freeman-Tukey double arcsine transformation among women with 1 prior low transverse cesarean section and women with unscarred uterus.
resultsWe reviewed 956 full text articles to include 69 studies. The pooled prevalence rate of uterine rupture is estimated to range between 2 and 9 out of 1000 women with 1 prior low transverse cesarean (5/1000; 95%CI 2-9/1000, 122/9000). The prevalence of uterine rupture among women with unscarred uterus is extremely low, reaching at most 0.7/100.000 (<1/100.000.000; 95%CI <1/100.000.000-0.7/100.000, 8/17.684).
conclusionsUterine rupture is a rare event during cervical ripening and labor induction with PGE2.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.