Evidence map›Paper›PMID 34228510›Full record

Trial reportJCO oncology practice2022

Using Geriatric Assessment to Guide Conversations Regarding Comorbidities Among Older Patients With Advanced Cancer.

Amber S Kleckner, Megan Wells, Lee A Kehoe, Nikesha J Gilmore, Huiwen Xu, Allison Magnuson, Richard F Dunne, Marielle Jensen-Battaglia, Mostafa R Mohamed, Mark A O'Rourke and 4 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in JCO oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02107443 (Improving Communication for Cancer Treatment), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02107443 nacompletednot on this map

Improving Communication for Cancer Treatment: Addressing Concerns of Older Cancer Patients and Caregivers

TypeinterventionalSponsorSupriya MohileRan2014 to 2020Enrolled546ConditionsAdult Solid Neoplasm, LymphomaArmsGeriatric Assessment Summary, Geriatric Assessment Targeted Recommendations, Geriatric Assessment (GA)
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Systemic Cancer Therapy: ASCO Guideline Update.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Amber S KlecknerDivision of Supportive Care in Cancer, Department of Surgery, University of Rochester Medical Center, Rochester, NY.ORCID 0000-0002-5088-1139
Megan WellsDepartment of Medicine, University of Rochester Medical Center, Rochester, NY.
Lee A KehoeDivision of Supportive Care in Cancer, Department of Surgery, University of Rochester Medical Center, Rochester, NY.
Nikesha J GilmoreDivision of Supportive Care in Cancer, Department of Surgery, University of Rochester Medical Center, Rochester, NY.
Huiwen XuDivision of Supportive Care in Cancer, Department of Surgery, University of Rochester Medical Center, Rochester, NY.ORCID 0000-0002-4033-0659
Allison MagnusonDepartment of Medicine, University of Rochester Medical Center, Rochester, NY.ORCID 0000-0002-0968-8265
Richard F DunneDepartment of Medicine, University of Rochester Medical Center, Rochester, NY.
Marielle Jensen-BattagliaDepartment of Public Health, University of Rochester Medical Center, Rochester, NY.ORCID 0000-0003-1941-9218
Mostafa R MohamedDepartment of Public Health, University of Rochester Medical Center, Rochester, NY.ORCID 0000-0003-2936-5794
Mark A O'RourkeNCORP of the Carolinas, Prisma Health Cancer Institute, Greenville, SC.ORCID 0000-0003-1707-6186
Nicholas J VogelzangNevada Cancer Research Foundation NCORP, Las Vegas, NV.ORCID 0000-0002-7665-6079
Elie G DibSt Joseph Mercy Cancer Center, Ann Arbor, MI.ORCID 0000-0002-7851-5165
Luke J PepponeDivision of Supportive Care in Cancer, Department of Surgery, University of Rochester Medical Center, Rochester, NY.
Supriya G MohileDepartment of Medicine, University of Rochester Medical Center, Rochester, NY.
University of Rochester Medical Center · USNevada Cancer Research Foundation · USPrisma Health · USTrinity Health Ann Arbor Hospital · US

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
Institutional Career Development CoreKL2TR001999 · NCATS · UNIVERSITY OF ROCHESTER · PI XIAO, JIN · 2016 to 2024
$5.2M
Geriatric Oncology Research Infrastructure to Improve Clinical CareR33AG059206 · NIA · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI WILLIAM DALE, Heidi Diana Klepin · 2020 to 2026
$5.1M
Clinical and Translational Cancer Control Research Training ProgramT32CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, Gary R Morrow · 2019 to 2026
$2.7M
A Patient-Oriented Research Program in Geriatric OncologyK24AG056589 · NIA · UNIVERSITY OF ROCHESTER · PI Supriya G. Mohile · 2018 to 2026
$1.5M
Mitigating Cancer-Related Cognitive Dysfunction in Older Adults with Breast CancerK76AG064394 · NIA · UNIVERSITY OF ROCHESTER · PI MAGNUSON, ALLISON MARIAN · 2019 to 2023
$1.3M
NCATS NIH HHS KL2 TR001999NCI NIH HHS T32 CA102618NCI NIH HHS UG1 CA189961NIA NIH HHS K24 AG056589NIA NIH HHS K76 AG064394NIA NIH HHS R33 AG059206
6 · The paper itself

Abstract

purposeOlder patients with advanced cancer often have comorbidities that can worsen their cancer and treatment outcomes. We assessed how a geriatric assessment (GA)-guided intervention can guide conversations about comorbidities among patients, oncologists, and caregivers.

methodsThis secondary analysis arose from a nationwide, multisite cluster-randomized trial (ClinicalTrials.gov identifier: NCT02107443). Eligible patients were ≥ 70 years, had advanced cancer (solid tumors or lymphoma), and had impairment in at least one GA domain (not including polypharmacy). Oncology practices (n = 30) were randomly assigned to usual care or intervention. All patients completed a GA; in the intervention arm, a GA summary with recommendations was provided to their oncologist. Patients completed an Older Americans Resources and Services Comorbidity questionnaire at screening. The clinical encounter following GA was audio-recorded, transcribed, and coded for topics related to comorbidities. Linear mixed models examined the effect of the intervention on the outcomes adjusting for practice site as a random effect.

resultsPatients (N = 541) were 76.6 ± 5.2 years old; 94.6% of patients had at least one comorbidity with an average of 3.2 ± 1.9. The intervention increased the average number of conversations regarding comorbidities per patient from 0.52 to 0.99 (

conclusionProviding oncologists with a GA-guided intervention enhanced communication regarding comorbidities.

Indexed as

NeoplasmsOncologistsAgedAged, 80 and overCommunicationComorbidityGeriatric AssessmentHumansUnited States

Identifiers

PMID34228510
PMCPMC8758128
OpenAlexW3182234674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.