Evidence map›Paper›PMID 34228344›Full record

ReviewMolecular diversity2022

Catalytic stereoselective Mannich-type reactions for construction of fluorinated compounds.

Minoo Dabiri, Noushin Farajinia Lehi, Reza Mohammadian

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular diversity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Minoo DabiriDepartment of Organic Chemistry and Oil, Faculty of Chemistry and Petroleum Sciences, Shahid Beheshti University, 1983969411, Tehran, Islamic Republic of Iran. m-dabiri@sbu.ac.ir.ORCID http://orcid.org/0000-0002-7086-4010
Noushin Farajinia LehiDepartment of Organic Chemistry and Oil, Faculty of Chemistry and Petroleum Sciences, Shahid Beheshti University, 1983969411, Tehran, Islamic Republic of Iran.
Reza MohammadianDepartment of Organic Chemistry and Oil, Faculty of Chemistry and Petroleum Sciences, Shahid Beheshti University, 1983969411, Tehran, Islamic Republic of Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For its unique role in developing and designing new bioactive materials and healthcare products, fluoro-organic compounds have attracted remarkable interest. Along with ever-increasing demand for a wider availability of fluorine-containing structural units, a large diversity of methods has been introduced to incorporate fluorine atoms specially in a stereoselective fashion. Among them, catalytic Mannich reaction can proceed with a broad variety of reactants and open clear paths for the synthesis of versatile amine synthons in the synthesis of natural product and pharmaceutical molecules. This review provides an overview of the employment of catalytic asymmetric Mannich reactions in the synthesis of fluorine-containing amine compounds and highlights the conceivable distinct mechanisms.

Indexed as

Biological ProductsFluorineAminesCatalysisStereoisomerismAminesBiological ProductsFluorineDiastereoselectiveEnantioselectiveFluorine compoundsMannich reactionMetal catalystOrganocatalysisThis review article is dedicated to Emeritus Prof. David Ian Davies (University of London King's College) as an appreciation for years of research and teaching

Identifiers

PMID34228344

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.