Evidence map›Paper›PMID 34228280›Full record

ReviewDrugs2021

Bupivacaine/Meloxicam Prolonged Release: A Review in Postoperative Pain.

Hannah A Blair

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05974423 phase4unknown statusnot on this mapstarted 2022, after this paper: background citation

Prospective Randomized Trial of Narcotic vs Non-Narcotic Pain Modulation Following a Labrum Repair

TypeinterventionalSponsorThe Cooper Health SystemRan2022 to 2025Enrolled60ConditionsPostoperative Pain, Acute, Opioid Use, Labral Tear, GlenoidArmsTylenol, Ibuprofen, and Oxycodone, Tylenol and Ibuprofen only
NCT07430085 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Postoperative Pain Outcomes After Use of Bupivacaine-Meloxicam Extended-Release Solution in Robot Assisted Total Knee Arthroplasty: A Prospective Study

TypeinterventionalSponsorAllegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)Ran2026 to 2028Enrolled150ConditionsPeriarticular Block, Osteoarthritis (OA), Osteoarthritis (OA) of the Knee, Pain After SurgeryArmsbupivacaine-meloxicam (extended release), Bupivacaine, Ketorolac, Lidocaine (drug)
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Nanotechnology for Pain Management.Journal of clinical medicine · 2024
    Review
  8. Article
  9. Article
  10. Functional Nanomaterials for the Treatment of Osteoarthritis.International journal of nanomedicine · 2024
    Review
  11. Structural mapping of NaNature communications · 2023
    Article
  12. Review
  13. Biomaterials and Regenerative Medicine in Pain Management.Current pain and headache reports · 2022
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Hannah A BlairSpringer Nature, Private Bag 65901, Mairangi Bay, Auckland, 0754, New Zealand. demail@springer.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prolonged-release (PR; as ascribed in the EU) or extended-release (as ascribed in the USA) bupivacaine/meloxicam (HTX-011; hereafter referred to as bupivacaine/meloxicam PR; Zynrelef

Indexed as

Analgesics, OpioidAnesthetics, LocalAnti-Inflammatory Agents, Non-SteroidalBupivacaineDelayed-Action PreparationsDrug CombinationsDrug InteractionsHumansMeloxicamPostoperative PainAnalgesics, OpioidAnesthetics, LocalAnti-Inflammatory Agents, Non-SteroidalBupivacaineDelayed-Action PreparationsDrug CombinationsMeloxicam

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.