ArticleMolecular biology reports2021
Inflammatory, antioxidant and glycemic status to different mode of high-intensity training in type 2 diabetes mellitus.
Article in Molecular biology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 9 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 9 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Comparative effects of long- and short-interval aerobic high-intensity interval training on glycemic control among individuals with type 2 diabetes: a network meta-analysis.BMC sports science, medicine & rehabilitation · 2026Pooled it
- Comparative effects of different intensities of aerobic and resistance exercise on glycemic control and cardiorespiratory fitness in middle-aged older patients with type 2 diabetes: a network meta-analysis.Frontiers in public health · 2026Pooled it
- The Anti-Inflammatory Effects of Resistance Training in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis.Biomolecules · 2025Pooled it
- Pooled it
- Effects of high-intensity intermittent exercise on glucose and lipid metabolism in type 2 diabetes patients: a systematic review and meta-analysis.Frontiers in endocrinology · 2024Pooled it
- Pooled it
- The effect of chronic high-intensity interval training programs on glycaemic control, aerobic resistance, and body composition in type 2 diabetic patients: a meta-analysis.Journal of endocrinological investigation · 2023Pooled it
- Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials.Journal of sport and health science · 2023Pooled it
- Effectiveness of Resistance Exercise on Inflammatory Biomarkers in Patients with Type 2 Diabetes Mellitus: A Systematic Review with Meta-Analysis.Diabetes & metabolism journal · 2023Pooled it
- The effects of high-intensity interval training on glucose metabolism, inflammatory responses, and functional recovery in patients with diabetic peripheral neuropathy.Frontiers in endocrinology · 2026Trial
- Redox-sensitive miRNAs and Humanin could mediate effects of exercise and astaxanthin on oxidative stress and inflammation in type 2 diabetes.Scientific reports · 2025Trial
- Exercise training reduces circulating cytokines in male patients with coronary artery disease and type 2 diabetes: A pilot study.Physiological reports · 2023Trial
- Mitochondria: the central hub linking exercise to enhanced cardiac function.Frontiers in physiology · 2026Review
- Impact of at-home circuit training on cardiovascular risk, functional capacity and quality of life in older adults with knee osteoarthritis and diabesity: a randomized controlled trial.AIMS public health · 2026Article
- The effect of different resistance exercise training intensities on cardiovascular risk factors: a systematic review and meta-analysis.European heart journal open · 2025Review
- High-Intensity Interval Training as Redox Medicine: Targeting Oxidative Stress and Antioxidant Adaptations in Cardiometabolic Disease Cohorts.Antioxidants (Basel, Switzerland) · 2025Review
- The Effect of Vitamin D3 Injection Combined With High-Intensity Interval Training on Excessive Autophagy in the Heart Tissue of Type 2 Diabetes-Induced Rats: An Analysis of the mTOR-Beclin-1-Fyco-1-Cathepsin D Pathway.Cardiovascular therapeutics · 2025Article
- The effects of resistance training on cardiovascular factors and anti-inflammation in diabetic rats.Heliyon · 2024Article
- Home-based circuit training improves blood lipid profile, liver function, musculoskeletal fitness, and health-related quality of life in overweight/obese older adult patients with knee osteoarthritis and type 2 diabetes: a randomized controlled trial during the COVID-19 pandemic.BMC sports science, medicine & rehabilitation · 2024Article
- Intervention Effects of Physical Activity on Type 2 Diabetic Patients Potentially Infected with COVID-19.Medicina (Kaunas, Lithuania) · 2023Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExercise has traditionally been used and prescribed as an effective and suitable way to treat type 2 diabetics Mellitus (T2DM). In this regard, we compared inflammatory, antioxidant, and glycemic status to different kinds of high-intensity interval training (strength training, HIIT, and HIIT + ST) in patients with T2DM. METHODS AND
resultsFifty-nine T2DM patients (age = 45-60 yrs) were randomly divided to strength training (ST) (n = 15), high intensity interval training (HIIT) (n = 16), HIIT + ST (n = 15) or served as control (CON) (n = 13) groups. Experimental groups performed three training sessions/week for 12 weeks. Inflammatory, antioxidant, glycemic factors, and anthropometric parameters were evaluated at baseline and after the 12 weeks of interventions. Training HIIT groups significantly improved antioxidant factors, lipid profile, and glycemic parameters (P ≤ 0.05). Interleukin 6 (IL-6), C-reactive protein (CRP), and tumor necrosis factor-α (TNF-α) significantly decreased in the three training groups. As a result of training, the overall inflammatory and antioxidant status were improved considerably in all three training groups compared to the CON group (P ≤ 0.05). In addition, there were significant differences in CRP at the follow-up values between ST and CON groups (P ≤ 0.05). Exercise time and TC were significantly improved in HIIT than in the CON group (P ≤ 0.05). The results showed a significant difference between the HIIT + ST group and the CON group in VO2
conclusionsOur results showed improvement in inflammatory factors, antioxidants, and glycemic parameters in all training groups regardless of their type. However, for more benefits in T2DM patients, combination exercises can be suggested.
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