Evidence map›Paper›PMID 34227466›Full record

ArticleeLife2021

Distinct signatures of calcium activity in brain mural cells.

Chaim Glück, Kim David Ferrari, Noemi Binini, Annika Keller, Aiman S Saab, Jillian L Stobart, Bruno Weber

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
  2. A pericyte chloride clamp mechanism governs capillary control of cerebral blood flow.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Cerebral capillary computation.American journal of physiology. Cell physiology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Eppur si muove: the dynamic brain pericyte.Fluids and barriers of the CNS · 2025
    Review
  13. Systemic nimodipine affects pericyte calcium signaling, resting hemodynamics and neurovascular coupling in healthy mouse brain.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
  14. Article
  15. Neurophotonics · 2025
    Article
  16. Article
  17. Pericyte Electrical Signalling and Brain Haemodynamics.Basic & clinical pharmacology & toxicology · 2025
    Review
  18. Article
  19. Article
  20. High-resolution vasomotion analysis reveals novel arteriole physiological features and progressive modulation of cerebral vascular networks by stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Chaim GlückInstitute of Pharmacology and Toxicology, University of Zurich, Zürich, Switzerland.ORCID 0000-0002-8754-9965
Kim David FerrariInstitute of Pharmacology and Toxicology, University of Zurich, Zürich, Switzerland.ORCID 0000-0002-7565-1276
Noemi BininiInstitute of Pharmacology and Toxicology, University of Zurich, Zürich, Switzerland.
Annika KellerNeuroscience Center Zurich, University and ETH Zurich, Zurich, Switzerland.ORCID 0000-0003-1466-3633
Aiman S SaabInstitute of Pharmacology and Toxicology, University of Zurich, Zürich, Switzerland.ORCID 0000-0003-3886-8369
Jillian L StobartInstitute of Pharmacology and Toxicology, University of Zurich, Zürich, Switzerland.
Bruno WeberInstitute of Pharmacology and Toxicology, University of Zurich, Zürich, Switzerland.ORCID 0000-0002-9089-0689
University of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pericytes have been implicated in various neuropathologies, yet little is known about their function and signaling pathways in health. Here, we characterized calcium dynamics of cortical mural cells in anesthetized or awake

Indexed as

AnimalsBrainCalciumCalcium SignalingCapillariesFemaleMaleMiceMuscle, Smooth, VascularMyocytes, Smooth MusclePericytesReceptor, Platelet-Derived Growth Factor betaVasoconstrictionVeinsCalciumReceptor, Platelet-Derived Growth Factor betacalcium signalingmouseMural cellsneurosciencepericytevasculature

Identifiers

PMID34227466
PMCPMC8294852
OpenAlexW3181691429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.