Evidence map›Paper›PMID 34227392›Full record

Trial reportJournal of the American Heart Association2021

Prognostic Effect of the SYNTAX Score on 10-Year Outcomes After Left Main Coronary Artery Revascularization in a Randomized Population: Insights From the Extended PRECOMBAT Trial.

Junghoon Lee, Jung-Min Ahn, Ju Hyeon Kim, Yeong Jin Jeong, Junho Hyun, Yujin Yang, Ji Sung Lee, Hanbit Park, Do-Yoon Kang, Pil Hyung Lee and 3 more

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Junghoon LeeDepartment of Cardiology Asan Medical CenterUniversity of Ulsan College of Medicine Seoul Korea.
Jung-Min AhnDepartment of Cardiology Asan Medical CenterUniversity of Ulsan College of Medicine Seoul Korea.
Ju Hyeon KimDepartment of Cardiology Asan Medical CenterUniversity of Ulsan College of Medicine Seoul Korea.
Yeong Jin JeongDepartment of Cardiology Asan Medical CenterUniversity of Ulsan College of Medicine Seoul Korea.
Junho HyunDepartment of Cardiology Asan Medical CenterUniversity of Ulsan College of Medicine Seoul Korea.
Yujin YangDepartment of Cardiology Asan Medical CenterUniversity of Ulsan College of Medicine Seoul Korea.
Ji Sung LeeDivision of Clinical Epidemiology and Biostatistics Center for Medical Research and Information Asan Medical CenterUniversity of Ulsan College of Medicine Seoul Korea.
Hanbit ParkDepartment of Cardiology Asan Medical CenterUniversity of Ulsan College of Medicine Seoul Korea.
Do-Yoon KangDepartment of Cardiology Asan Medical CenterUniversity of Ulsan College of Medicine Seoul Korea.
Pil Hyung LeeDepartment of Cardiology Asan Medical CenterUniversity of Ulsan College of Medicine Seoul Korea.
Duk-Woo ParkDepartment of Cardiology Asan Medical CenterUniversity of Ulsan College of Medicine Seoul Korea.
Seung-Jung ParkDepartment of Cardiology Asan Medical CenterUniversity of Ulsan College of Medicine Seoul Korea.
on the behalf of the PRECOMBAT Investigators
Ulsan College · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The long-term prognostic effect of the SYNTAX (Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery) score (SS) after percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) for left main coronary artery disease is controversial. Methods and Results In the PRECOMBAT (Premier of Randomized Comparison of Bypass Surgery Versus Angioplasty Using Sirolimus-Eluting Stent in Patients With Left Main Coronary Artery Disease) trial, 600 patients with left main coronary artery disease were randomized to undergo PCI with drug-eluting stents (n=300) or CABG (n=300). We compared 10-year outcomes after PCI and CABG according to SS categories and evaluated the predictive value of SS in each revascularization arm. The primary outcome was a major adverse cardiac or cerebrovascular event (composite of death, myocardial infarction, stroke, or ischemia-driven target-vessel revascularization) at 10 years. Among 566 patients with valid SS measurement at baseline, 240 (42.4%) had low SS, 200 (35.3%) had intermediate SS, and 126 (22.3%) had high SS. The 10-year rates of major adverse cardiac or cerebrovascular events were not significantly different between PCI and CABG in low (21.6% versus 22.2%,

Indexed as

Drug-Eluting StentsCoronary Artery DiseaseCoronary VesselsFemaleFollow-Up StudiesHumansImmunosuppressive AgentsMaleMiddle AgedPercutaneous Coronary InterventionPrognosisProspective StudiesRepublic of KoreaRisk AssessmentRisk FactorsSirolimusImmunosuppressive AgentsSirolimuscoronary artery bypass graftcoronary artery diseasepercutaneous coronary intervention

Identifiers

PMID34227392
PMCPMC8483455
OpenAlexW3178642823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.