Evidence map›Paper›PMID 34227175›Full record

ArticleThe oncologist2021

Prescription Opioids Dispensed to Patients with Cancer with Bone Metastasis: 2011-2017.

Hao Zhang, Judith Paice, Russell Portenoy, Eduardo Bruera, M Carrington Reid, Yuhua Bao

Abstract read
In one paragraph

Article in The oncologist, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Healthcare provider perceptions and reported practices regarding opioid prescription for patients with chronic cancer pain.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Improvement in patient-reported pain among patients with metastatic cancer and its association with opioid prescribing.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. The US Cancer Pain Crisis and the Global Pain Divide: Can Two Wrongs Make It Right?Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2022
    Article
  14. Management of pain in the cancer patient.Frontiers in pain research (Lausanne, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hao ZhangDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0002-2379-1584
Judith PaiceDivision of Hematology-Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Russell PortenoyMJHS Institute for Innovation in Palliative Care, New York, New York, USA.
Eduardo BrueraDepartment of Palliative, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
M Carrington ReidDivision of Geriatrics and Palliative Care, Department of Medicine, Weill Cornell Medicine, New York, New York, Texas, USA.
Yuhua BaoDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.

Funding

Utilization of health services after engagement with opioid use disorder (OUD) treatment provider by individuals with and without post-traumatic stress disorderP30DA040500 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI ZACHARY Franklin MEISEL · 2015 to 2026
$20.7M
Pilot CoreP30AG022845 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Manney Carrington Reid · 2003 to 2026
$15.2M
Reid Aging and Pain Research Training ProgramK24AG053462 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI REID, MANNEY CARRINGTON · 2016 to 2025
$1.8M
NIA NIH HHS K24 AG053462NIA NIH HHS P30 AG022845NIDA NIH HHS P30 DA040500
6 · The paper itself

Abstract

Opioid therapy is a first-line approach for moderate-to-severe pain associated with cancer with bone metastasis (CBM). The decade-long decline in opioid prescribing in the U.S. would not be expected to affect patients with CBM. We investigated trends in opioids dispensed to patients with CBM using data from a large commercial claims database. From 2011 quarter 2 to 2017 quarter 4, the percentage of patients with CBM prescribed at least 1 day of opioids in a quarter declined from 28.1% to 24.5% (p < .001) for privately insured patients aged 18-64 years and from 39.1% to 30.5% (p < .001) for Medicare Advantage (MA) patients aged 65 years or older. Among patients with at least 1 day of opioids in a quarter, the average morphine milligram equivalents dispensed declined by 37% and 11% (p < .001 for both) for privately insured and MA patients, respectively. Our findings raise concerns about potential unintended consequences related to population-level reduction in opioid prescribing.

Indexed as

Analgesics, OpioidBone NeoplasmsAgedHumansMedicarePractice Patterns, Physicians'PrescriptionsUnited StatesAnalgesics, Opioid

Identifiers

PMID34227175
PMCPMC8488796

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.