Evidence map›Paper›PMID 34226877›Full record

ArticleMedicina clinica (English ed.)2021

Application of validated severity scores for pneumonia caused by SARS-CoV-2.

Violeta Esteban Ronda, Sandra Ruiz Alcaraz, Paloma Ruiz Torregrosa, Mario Giménez Suau, Ester Nofuentes Pérez, José Manuel León Ramírez, Mariano Andrés, Óscar Moreno-Pérez, Alfredo Candela Blanes, Joan Gil Carbonell and 1 more

Abstract read
In one paragraph

Article in Medicina clinica (English ed.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Performance of Risk Scores in SARS-CoV-2 Infection: A Retrospective Study.International journal of environmental research and public health · 2025
    Observational
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. The Usefulness of the COVID-GRAM Score in Predicting the Outcomes of Study Population with COVID-19.International journal of environmental research and public health · 2022
    Article
  12. Article
  13. External Validation and Recalibration of the CURB-65 and PSI for Predicting 30-Day Mortality and Critical Care Intervention in Multiethnic Patients with COVID-19.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Article
  14. Epidemiology and Clinical Impact of Confirmed Respiratory Viral Infections in Solid Organ Transplant Recipients.Transplant infectious disease : an official journal of the Transplantation Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Violeta Esteban RondaServicio de Neumología, Hospital General Universitario de Alicante, Alicante, Spain.
Sandra Ruiz AlcarazServicio de Neumología, Hospital General Universitario de Alicante, Alicante, Spain.
Paloma Ruiz TorregrosaServicio de Neumología, Hospital General Universitario de Alicante, Alicante, Spain.
Mario Giménez SuauServicio de Neumología, Hospital General Universitario de Alicante, Alicante, Spain.
Ester Nofuentes PérezServicio de Neumología, Hospital General Universitario de Alicante, Alicante, Spain.
José Manuel León RamírezServicio de Neumología, Hospital General Universitario de Alicante, Alicante, Spain.
Mariano AndrésServicio de Reumatología, Hospital General Universitario de Alicante, Alicante, Spain.
Óscar Moreno-PérezServicio de Endocrinología y Nutrición, Hospital General Universitario de Alicante, Alicante, Spain.
Alfredo Candela BlanesServicio de Neumología, Hospital General Universitario de Alicante, Alicante, Spain.
Joan Gil CarbonellServicio de Neumología, Hospital General Universitario de Alicante, Alicante, Spain.
Esperanza Merino de LucasUnidad de Enfermedades Infecciosas, Hospital General Universitario de Alicante, Alicante, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCompare the accuracy of PSI, CURB-65, MuLBSTA and COVID-GRAM prognostic scores to predict mortality, the need for invasive mechanical ventilation (IMV) in patients with pneumonia caused by SARS-CoV-2 and assess the coexistence of bacterial respiratory tract infection during admission.

methodsRetrospective observational study that included hospitalized adults with pneumonia caused by SARS-CoV-2 from 15/03 to 15/05/2020. We excluded immunocompromised patients, nursing home residents and those admitted in the previous 14 days for another reasons. Analysis of ROC curves was performed, calculating the area under the curve for the different scales, as well as sensitivity, specificity and predictive values.

results208 patients were enrolled, aged 63 ± 17 years, 577% were men. 38 patients were admitted to ICU (235%), of these patients 33 required IMV (868%), with an overall mortality of 125%. Area under the ROC curves for mortality of the scores were: PSI 082 (95% CI 073-091), CURB-65 082 (073-091), MuLBSTA 072 (062-081) and COVID-GRAM 086 (070-1). Area under the curve for needing IMV was: PSI 073 (95% CI 064-082), CURB-65 066 (055-077), MuLBSTA 078 (069-086) and COVID-GRAM 076 (067-085), respectively. Patients with bacterial co-infections of the respiratory tract were 20 (9,6%), the most frequent strains being

conclusionsIn our study, the COVID-GRAM score was the most accurate to identify patients with higher mortality with pneumonia caused by SARS-CoV-2; however, none of these scores accurately predicts the need for IMV with ICU admission. 10% of patients admitted presented bacterial respiratory co-infection.

Indexed as

CoronavirusCOVID-19PenumoniaSeverity scores

Identifiers

PMID34226877
PMCPMC8241713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.