ReviewProcess safety and environmental protection : transactions of the Institution of Chemical Engineers, Part B2021
A critical review on environmental presence of pharmaceutical drugs tested for the covid-19 treatment.
Review in Process safety and environmental protection : transactions of the Institution of Chemical Engineers, Part B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.
- Literature Review: Evaluation of Drug Removal Techniques in Municipal and Hospital Wastewater.International journal of environmental research and public health · 2022Pooled it
- Pseudomonas sp. MSW2-Mediated Biodegradation of Pharmaceutical Micropollutants: Experimental and In Silico Investigations.Current microbiology · 2025Article
- COVID-19 pandemic-related drugs and microplastics from mask fibers jointly affect soil functions and processes.Environmental science and pollution research international · 2024Article
- Robust CA-GO-TiOPolymers · 2024Article
- Natural and Natural-Based Polymers: Recent Developments in Management of Emerging Pollutants.Polymers · 2023Review
- Special Issue "Microbial Biodegradation and Biotransformation".Microorganisms · 2023Article
- Are we ready to combat the ecotoxicity of COVID-19 pharmaceuticals? An in silico aquatic risk assessment.Aquatic toxicology (Amsterdam, Netherlands) · 2023Article
- Study of the Effect of Antibiotics in Drinking Water on the Content of Antioxidant Compounds in Red Wines.Molecules (Basel, Switzerland) · 2022Article
- A sustainable approach for the removal methods and analytical determination methods of antiviral drugs from water/wastewater: A review.Journal of water process engineering · 2022Review
- Article
- Favipiravir (SARS-CoV-2) degradation impurities: Identification and route of degradation mechanism in the finished solid dosage form using LC/LC-MS method.Biomedical chromatography : BMC · 2022Article
- Safety, environmental and risk management related to Covid-19.Process safety and environmental protection : transactions of the Institution of Chemical Engineers, Part B · 2022Article
- Pharmaceutical compounds used in the COVID-19 pandemic: A review of their presence in water and treatment techniques for their elimination.The Science of the total environment · 2022Review
- Hydroxychloroquine Adsorption in Aqueous Medium Using Clinoptilolite Zeolite.Water, air, and soil pollution · 2022Article
- COVID-19 drugs in aquatic systems: a review.Environmental chemistry letters · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
On March 11, 2020, the World Health Organization (WHO) declared COVID-19 a pandemic. The outbreak caused a worldwide impact, becoming a health threat to the general population and its professionals. To date, there are no specific antiviral treatments or vaccines for the COVID-19 infection, however, some drugs are being clinically tested. The use of these drugs on large scale raises great concern about their imminent environmental risk, since the elimination of these compounds by feces and urine associated with the inefficiency of sewage treatment plants in their removal can result in their persistence in the environment, putting in risk the health of humans and of other species. Thus, the goal of this work was to conduct a review of other studies that evaluated the presence of the drugs chloroquine, hydroxychloroquine, azithromycin, ivermectin, dexamethasone, remdesivir, favipiravir and some HIV antivirals in the environment. The research indicated the presence of these drugs in the environment in different regions, with concentration data that could serve as a basis for further comparative studies following the pandemic.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.