Evidence map›Paper›PMID 34226656›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2021

Dissociable control of μ-opioid-driven hyperphagia vs. food impulsivity across subregions of medial prefrontal, orbitofrontal, and insular cortex.

Juliana L Giacomini, Emma Geiduschek, Ryan A Selleck, Ken Sadeghian, Brian A Baldo

Open access · bronzeAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. A ventral hippocampus to nucleus accumbens pathway regulates impulsivity in male but not female rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  2. Optogenetic Hedonic Hotspots in the Orbitofrontal Cortex and Insula: Causing Enhancement of Sweetness "Liking".The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  3. Article
  4. A ventral hippocampus to nucleus accumbens pathway regulates impulsivity.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. The Role of the Rat Prefrontal Cortex and Sex Differences in Decision-Making.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Juliana L GiacominiGraduate Program in Cellular and Molecular Biology, Physiology Training Program, University of Wisconsin-Madison, Madison, WI, USA.
Emma GeiduschekNeuroscience Training Program, University of Wisconsin-Madison, Madison, WI, USA.
Ryan A SelleckDepartment of Psychological Science, Albion College, Albion, MI, USA.
Ken SadeghianDepartment of Psychiatry, University of Wisconsin-Madison, Madison, WI, USA.
Brian A BaldoNeuroscience Training Program, University of Wisconsin-Madison, Madison, WI, USA. babaldo@wisc.edu.
University of Wisconsin–Madison · USAlbion College · US

Funding

Prefrontal cortex-hypothalmus interactions and feedingR01MH074723 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI BALDO, BRIAN A · 2007 to 2019
$3.4M
NIMH NIH HHS R01 MH074723
6 · The paper itself

Abstract

This study explored potentially dissociable functions of mu-opioid receptor (µ-OR) signaling across different cortical territories in the control of anticipatory activity directed toward palatable food, consumption, and impulsive food-seeking behavior in male rats. The µ-OR agonist, DAMGO ([D-Ala

Indexed as

Analgesics, OpioidHyperphagiaAnimalsImpulsive BehaviorMalePrefrontal CortexRatsRats, Sprague-DawleyAnalgesics, Opioid

Identifiers

PMID34226656
PMCPMC8429588
OpenAlexW3177598301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.