Evidence map›Paper›PMID 34226495›Full record

ReviewTranslational psychiatry2021

Mental health and music engagement: review, framework, and guidelines for future studies.

Daniel E Gustavson, Peyton L Coleman, John R Iversen, Hermine H Maes, Reyna L Gordon, Miriam D Lense

Abstract readReview
In one paragraph

Review in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effects of music-based interventions on cancer-related pain, fatigue, and distress: an overview of systematic reviews.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Review
  8. Adolescent music engagement is associated with less alcohol consumption and substance experimentation 5-11 years later: A genetically informative study.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. The Music and Mental Health Project: uniting primary health care globally through music.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel E GustavsonDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. daniel.e.gustavson@vumc.org.ORCID 0000-0002-1470-4928
Peyton L ColemanDepartment of Otolaryngology - Head & Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0001-5388-6886
John R IversenSwartz Center for Computational Neuroscience, Institute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Hermine H MaesDepartment of Human and Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
Reyna L GordonVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Miriam D LenseVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lea K Davis · 2020 to 2026
$10.3M
Biomarkers of Rhythmic Communication: Integrating Foundational and Translational ApproachesDP2HD098859 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GORDON, REYNA LEIGH · 2018 to 2018
$2.4M
Musical Rhythm Sensitivity to Scaffold Social Engagement in Autism Spectrum DisorderR61MH123029 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JONES, WARREN, LENSE, MIRIAM · 2019 to 2020
$1.2M
Large-scale nested studies of the impact of music on brain and behavioral developmentR01AA028411 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI IVERSEN, JOHN REHNER · 2019 to 2021
$825k
Social Rhythmic Entrainment and Language Development in Autism Spectrum DisordersR21DC016710 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI LENSE, MIRIAM · 2018 to 2020
$540k
The Role of Executive Functions in Cognitive Aging and Risk for Mild Cognitive ImpairmentR03AG065643 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GUSTAVSON, DANIEL · 2020 to 2021
$173k
National Endowment for the Arts (NEA) 1855526-38National Science Foundation (NSF) 1926794NIAAA NIH HHS R01 AA028411NIA NIH HHS R03 AG065643NICHD NIH HHS DP2 HD098859NICHD NIH HHS P50 HD103537NIDCD NIH HHS R21 DC016710NIMH NIH HHS R61 MH123029U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) DP2HD098859U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) R03AG065643U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) R01AA028411
6 · The paper itself

Abstract

Is engaging with music good for your mental health? This question has long been the topic of empirical clinical and nonclinical investigations, with studies indicating positive associations between music engagement and quality of life, reduced depression or anxiety symptoms, and less frequent substance use. However, many earlier investigations were limited by small populations and methodological limitations, and it has also been suggested that aspects of music engagement may even be associated with worse mental health outcomes. The purpose of this scoping review is first to summarize the existing state of music engagement and mental health studies, identifying their strengths and weaknesses. We focus on broad domains of mental health diagnoses including internalizing psychopathology (e.g., depression and anxiety symptoms and diagnoses), externalizing psychopathology (e.g., substance use), and thought disorders (e.g., schizophrenia). Second, we propose a theoretical model to inform future work that describes the importance of simultaneously considering music-mental health associations at the levels of (1) correlated genetic and/or environmental influences vs. (bi)directional associations, (2) interactions with genetic risk factors, (3) treatment efficacy, and (4) mediation through brain structure and function. Finally, we describe how recent advances in large-scale data collection, including genetic, neuroimaging, and electronic health record studies, allow for a more rigorous examination of these associations that can also elucidate their neurobiological substrates.

Indexed as

Mental DisordersMusicMusic TherapyAnxietyHumansMental HealthQuality of Life

Identifiers

PMID34226495
PMCPMC8257764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.