ArticleJournal of animal science and biotechnology2021
Dietary oregano essential oil supplementation improves intestinal functions and alters gut microbiota in late-phase laying hens.
Article in Journal of animal science and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed, 139 citations in OpenAlex.
- A meta-analysis ofVeterinary and animal science · 2026Review
- Optimizing low-crude protein diets with essential oils and sodium butyrate to maintain productive performance and improve intestinal integrity in 58- to 69-wk-old laying hens.Poultry science · 2026Article
- Phytogenic as a natural resource for gut health management: a sustainable strategy for modern poultry production.Veterinary and animal science · 2026Review
- Dietary thyme essential oil supplementation improves production performance, egg quality, antioxidant status, and intestinal health in late-phase laying hens.Poultry science · 2026Article
- Article
- Multi-omics analysis reveals that puerarin modulates the gut-liver axis to improve hepatic health in aged laying hens.BMC genomics · 2026Article
- Nutritional enrichment of eggs through essential oil-supplemented laying hen diets and associations with intestinal microbiota.Food science of animal resources · 2026Article
- Effects of Dietary Supplementation with α-Mangostin on Oviduct Inflammation and Eggshell Quality in Aging Laying Hens.Animals : an open access journal from MDPI · 2026Article
- Optimizing eggshell quality in extended laying periods: Insights and strategies.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Review
- LateiScience · 2026Article
- Baicalin alleviates uterine inflammaging and improves eggshell quality in aged laying hens.Frontiers in immunology · 2026Article
- Architecture, permeability, disruption dynamics and remodeling of tight junction proteins: Implications for performance, health, and welfare of the broiler chicken.Poultry science · 2026Review
- Metabolic and Endocrine Markers of Oregano Essential Oil Effects on Antibacterial Immunity, Reproductive Function, Nutritional Status, and Production Performance of Late-Phase Laying Hens.Veterinary sciences · 2025Article
- RNA Sequencing-Based Transcriptome Analysis of Liver in Laying Hens Supplemented with Dietary ProbioticVeterinary sciences · 2025Article
- Egg exosome miR-145-5p decreases mitochondrial ROS to protect chicken embryo hepatocytes against apoptosis through targeting MAPK10.Journal of animal science and biotechnology · 2025Article
- The Effects of Fishmeal Replacement with Degossypolled Cottonseed Protein on Growth, Serum Biochemistry, Endocrine Responses, Lipid Metabolism, and Antioxidant and Immune Responses in Black Carp (Animals : an open access journal from MDPI · 2025Article
- Comparative Effects of Organic and Nano-Selenium on Egg Quality and Antioxidant Capacity in Layer Hens.Foods (Basel, Switzerland) · 2025Article
- Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickens.Veterinary world · 2025Article
- Dietary supplementation of oregano essential oil, lauric acid, and a multi-enzyme complex enhances productivity, metabolic status, and gut health in Dagu breeder hens.Journal of animal science · 2025Article
- Dietary Bazhen San solid-state fermentation product improves laying performance, immunity and intestinal health in laying hens during the late laying period.Frontiers in immunology · 2025Article
3 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundDietary essential oil (EO) supplementation can exert favorable effects on gut health in broilers. However, it is unknown whether EO could improve intestinal functions, consequently beneficial for egg performance and quality in late-phase laying hens. This study was aimed to investigate the potential effects of EO on production performance, egg quality, intestinal health and ileal microbiota of hens in the late phase of production. A total of 288 60-week-old Hy-line Brown laying hens were randomly divided into 4 groups and fed a basal diet (control) or basal diets supplemented with oregano EO at 100, 200 and 400 mg/kg (EO100, EO200 and EO400).
resultsDietary EO supplementation resulted in a quadratic decrease (P < 0.05) in feed conversion ratio with lower (P < 0.05) feed conversion ratio in EO200 group than the control during weeks 9-12 and 1-12 of the trial. Compared to the control, EO addition resulted in higher (P < 0.05) eggshell thickness at the end of week. 4, 8 and 12 and higher (P < 0.05) chymotrypsin activity. There was a quadratic elevation (P < 0.05) in ileal chymotrypsin and lipase activity, along with a linear increase in villus height to crypt depth ratio. Quadratic declines (P < 0.05) in mRNA expression of IL-1β, TNF-α, IFN-γ and TLR-4, concurrent with a linear and quadratic increase (P < 0.05) in ZO-1 expression were identified in the ileum with EO addition. These favorable effects were maximized at medium dosage (200 mg/kg) of EO addition and intestinal microbial composition in the control and EO200 groups were assessed. Dietary EO addition increased (P < 0.05) the abundances of Burkholderiales, Actinobacteria, Bifidobacteriales, Enterococcaceae and Bacillaceae, whereas decreased Shigella abundance in the ileum.
conclusionsDietary EO addition could enhance digestive enzyme activity, improve gut morphology, epithelial barrier functions and modulate mucosal immune status by altering microbial composition, thus favoring feed efficiency and eggshell quality of late-phase laying hens.
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