Trial reportEnvironmental health : a global access science source2021
Portable HEPA filter air cleaner use during pregnancy and children's behavior problem scores: a secondary analysis of the UGAAR randomized controlled trial.
Trial report in Environmental health : a global access science source, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01741051 (A Randomized Air Filter Intervention Study of Air Pollution and Fetal Growth in a Highly Polluted Community), which is not on this map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Air Filter Intervention Study of Air Pollution and Fetal Growth in a Highly Polluted Community
Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Analysis of sources and sinks of indoor particulate matter reveals insights into the real-world efficacy of portable air cleaners in a randomized intervention trial.The Science of the total environment · 2025Trial
- Health Benefits of Air Purification: A Systematic Review.Environment & health (Washington, D.C.) · 2026Review
- Cognitive benefits of air purification among schoolchildren: A randomized, double-blind, crossover trial.Innovation (Cambridge (Mass.)) · 2026Article
- Associations of prenatal fine particulate matter mixtures with neurodevelopmental outcomes in early childhood: component- and source-specific insights.Particle and fibre toxicology · 2026Article
- Mapping multilevel adaptation response to protect maternal and child health from climate change impacts: A scoping review.iScience · 2025Review
- Interventions to reduce the effects of air pollution and of extreme heat on maternal, newborn, and child health outcomes: a mapping of the literature.Journal of global health · 2025Review
- Bio-inspired designs: leveraging biological brilliance in mechanical engineering-an overview.3 Biotech · 2024Review
- Sensitivity analysis for live birth bias in the Ulaanbaatar Gestation and Air Pollution Research study.Environmental epidemiology (Philadelphia, Pa.) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundDevelopmental exposure to particulate matter (PM) air pollution may impair children's behaviors. Our objectives were to quantify the impact of reducing indoor PM using portable HEPA filter air cleaners during pregnancy on behavioral problems in children and to assess associations between indoor fine PM (PM
methodsThis is a secondary analysis of a single-blind parallel-group randomized controlled trial in which we randomly assigned 540 non-smoking pregnant women to receive 1 or 2 HEPA filter air cleaners or no air cleaners. We administered the Behavior Assessment System for Children (BASC-3) to caregivers when children were a mean age of 23 months, and again at a mean age of 48 months. Primary outcomes were the four BASC-3 composite scales: externalizing problems, internalizing problems, adaptive skills, and the behavioral symptoms index. We imputed missing data using multiple imputation with chained equations. The primary analysis was by intention-to-treat. In a secondary analysis, we evaluated associations between BASC-3 composite indices and modeled trimester-specific PM
resultsWe enrolled participants at a median of 11 weeks gestation. After excluding miscarriages, still births and neonatal deaths, our analysis included 478 children (233 control and 245 intervention). We observed no differences in the mean BASC-3 scores between treatment groups. An interquartile increase (20.1 µg/m
conclusionWe found no benefit of reducing indoor particulate air pollution during pregnancy on parent-reported behaviors in children. Associations between indoor PM
trial registrationClinicalTrials.gov: NCT01741051.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.