Evidence map›Paper›PMID 34225756›Full record

ArticleMalaria journal2021

Malaria prevalence and long-lasting insecticidal net use in rural western Uganda: results of a cross-sectional survey conducted in an area of highly variable malaria transmission intensity.

Claire M Cote, Varun Goel, Rabbison Muhindo, Emmanuel Baguma, Moses Ntaro, Bonnie E Shook-Sa, Raquel Reyes, Sarah G Staedke, Edgar M Mulogo, Ross M Boyce

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Permethrin-Treated Baby Wraps for the Prevention of Malaria.The New England journal of medicine · 2025
    Trial
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  10. Differential Influence of Environmental Factors on Malaria Due to Vector Control Interventions in Uganda.International journal of environmental research and public health · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Claire M CoteGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Varun GoelDepartment of Geography, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Rabbison MuhindoDepartment of Community Health, Mbarara University of Science and Technology, Mbarara, Uganda.
Emmanuel BagumaDepartment of Community Health, Mbarara University of Science and Technology, Mbarara, Uganda.
Moses NtaroDepartment of Community Health, Mbarara University of Science and Technology, Mbarara, Uganda.
Bonnie E Shook-SaDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Raquel ReyesDivision of Hospital Medicine, UNC School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Sarah G StaedkeLondon School of Hygiene and Tropical Medicine, London, UK.
Edgar M MulogoDepartment of Community Health, Mbarara University of Science and Technology, Mbarara, Uganda.
Ross M BoyceDepartment of Community Health, Mbarara University of Science and Technology, Mbarara, Uganda. roboyce@med.unc.edu.ORCID http://orcid.org/0000-0002-9489-6324
University of North Carolina at Chapel Hill · USMbarara University of Science and Technology · UGLondon School of Hygiene & Tropical Medicine · GB

Funding

Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Serial Killers to Mosquitos: The Spatial Targeting of Larval habitats in rural Uganda using geographic ProfilingK23AI141764 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOYCE, ROSS MATHEW · 2019 to 2023
$944k
National Institute of Allergy and Infectious Diseases K23AI141764NIAID NIH HHS K23 AI141764NICHD NIH HHS P2C HD050924
6 · The paper itself

Abstract

backgroundLong-lasting insecticidal nets (LLINs) remain a cornerstone of malaria control, but strategies to sustain universal coverage and high rates of use are not well-defined. A more complete understanding of context-specific factors, including transmission intensity and access to health facilities, may inform sub-district distribution approaches and tailored messaging campaigns.

methodsA cross-sectional survey of 2190 households was conducted in a single sub-county of western Uganda that experiences highly variable malaria transmission intensity. The survey was carried out approximately 3 years after the most recent mass distribution campaign. At each household, study staff documented reported LLIN use and source among children 2 to 10 years of age and performed a malaria rapid diagnostic test. Elevation and distance to the nearest health facility was estimated for each household. Associations between parasite prevalence and LLIN use were estimated from log binomial regression models with elevation and distance to clinic being the primary variables of interest.

resultsOverall, 6.8% (148 of 2170) of children age 2-10 years of age had a positive RDT result, yielding a weighted estimate of 5.8% (95% confidence interval [CI] 5.4-6.2%). There was substantial variability in the positivity rates among villages, with the highest elevation villages having lower prevalence than lowest-elevation villages (p < .001). Only 64.7% (95% CI 64.0-65.5%) of children were reported to have slept under a LLIN the previous night. Compared to those living < 1 km from a health centre, households at ≥ 2 km were less likely to report the child sleeping under a LLIN (RR 0.86, 95% CI 0.83-0.89, p < .001). Households located farther from a health centre received a higher proportion of LLINs from government distributions compared to households living closer to health centres.

conclusionsLLIN use and sourcing was correlated with household elevation and estimated distance to the nearest health facility. The findings suggest that current facility-based distribution strategies are limited in their reach. More frequent mass distribution campaigns and complementary approaches are likely required to maintain universal LLIN coverage and high rates of use among children in rural Uganda.

Indexed as

Cross-Sectional StudiesInsecticide-Treated BednetsMalariaMosquito ControlPrevalenceRural PopulationUgandaInsecticide-treated bed netsMalariaMosquito netsPlasmodiumUganda

Identifiers

PMID34225756
PMCPMC8256478
OpenAlexW3182616029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.