Evidence map›Paper›PMID 34225746›Full record

ArticleJournal of neuroinflammation2021

The potential roles of m

Qi Li, Shaohong Wen, Weizhen Ye, Shunying Zhao, Xiangrong Liu

Open access · goldAbstract read
In one paragraph

Article in Journal of neuroinflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. The mCells · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. The Signature of Serum Modified Nucleosides in Uveitis.Investigative ophthalmology & visual science · 2025
    Article
  11. Review
  12. Article
  13. Research advances in mFrontiers in cell and developmental biology · 2025
    Review
  14. Single-cell mNature neuroscience · 2024
    Article
  15. Article
  16. Article
  17. Biology · 2024
    Article
  18. Article
  19. Article
  20. Heliyon · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qi LiChina National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, 119 South Fourth Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China.
Shaohong WenChina National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, 119 South Fourth Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China.
Weizhen YeChina National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, 119 South Fourth Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China.
Shunying ZhaoChina National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, 119 South Fourth Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China.
Xiangrong LiuChina National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, 119 South Fourth Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China. lxrpumc@163.com.ORCID http://orcid.org/0000-0003-2406-7587
Capital Medical University · CN

Funding

National Natural Science Foundation of China 81471209National Natural Science Foundation of China 81871021
6 · The paper itself

Abstract

backgroundMicroglia are key regulators of the inflammatory response in the brain. Adenosine in RNAs can be converted to m

methodsPrimary rat microglia were differentiated into pro-inflammatory M1-like (M1-L), anti-inflammatory M2-like (M2-L), and resting, unstimulated (M0-L) phenotypes. m

resultsA total of 1588 mRNAs and 340 lncRNAs, 315 mRNAs and 38 lncRNAs, and 521 mRNAs and 244 lncRNAs were differentially m

conclusionsThese findings identify a distinct m

Indexed as

AdenosineAnimalsAnimals, NewbornCells, CulturedInflammation MediatorsMicrogliaRatsRats, Sprague-DawleyRNA, MessengerTranscriptomeAdenosineInflammation MediatorsN-methyladenosineRNA, MessengerBioinformatics analysisInflammatory responsem6A lncRNAm6A mRNAMethylated m6A RNA immunoprecipitationMicroarrayMicrogliaPhenotypePolarization

Identifiers

PMID34225746
PMCPMC8259013
OpenAlexW3178864904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.