Evidence map›Paper›PMID 34225213›Full record

ArticleUltrasonics sonochemistry2021

Recovery of β-carotene from pumpkin using switchable natural deep eutectic solvents.

Alena Stupar, Vanja Šeregelj, Bernardo Dias Ribeiro, Lato Pezo, Aleksandra Cvetanović, Aleksandra Mišan, Isabel Marrucho

Abstract read
In one paragraph

Article in Ultrasonics sonochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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  17. Recovery of Cembratrien-Diols from Waste Tobacco (Molecules (Basel, Switzerland) · 2024
    Article
  18. Tailor-made solvents for microbial carotenoids recovery.Applied microbiology and biotechnology · 2024
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alena StuparUniversity of Novi Sad, Institute of Food Technology, Bulevar cara Lazara 1, 21000 Novi Sad, Serbia. Electronic address: alena.tomsik@fins.uns.ac.rs.
Vanja ŠeregeljUniversity of Novi Sad, Institute of Food Technology, Institute of Food Technology, Bulevar cara Lazara, 121000 Novi Sad, Serbia, Republic of Serbia.
Bernardo Dias RibeiroEscola de Quimica, Universidade Federal do Rio de Janeiro, Av Horacio Macedo, CT, Bl.E, 101, 21941598 Rio de Janeiro, Brazil; Centro de Química Estrutural and Departamento de Engenharia Química, Instituto Superior Tecnico, Universidade de Lisboa, Avenida Rovisco Pais, 1049-001 Lisboa, Portugal.
Lato PezoUniversity of Belgrade, Institute of General and Physical Chemistry, Studentski trg 12/V, 11000 Belgrade, Serbia.
Aleksandra CvetanovićUniversity of Novi Sad, Institute of Food Technology, Institute of Food Technology, Bulevar cara Lazara, 121000 Novi Sad, Serbia, Republic of Serbia.
Aleksandra MišanUniversity of Novi Sad, Institute of Food Technology, Bulevar cara Lazara 1, 21000 Novi Sad, Serbia.
Isabel MarruchoCentro de Química Estrutural and Departamento de Engenharia Química, Instituto Superior Tecnico, Universidade de Lisboa, Avenida Rovisco Pais, 1049-001 Lisboa, Portugal. Electronic address: isabel.marrucho@tecnico.ulisboa.pt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present research was to develop green and sustainable extraction procedure for β-carotene recovery from pumpkin. A series of hydrophobic natural deep eutectic solvents (NADESs) based onfatty acids were prepared to establish high extraction efficiency of β-carotene and to increase stability of extracted carotenoids from the pumpkin. To intensify extraction process, NADES composed of C8 and C10 fatty acids (3:1) was selected and coupled with ultrasound assisted extraction. Response surface methodology and artificial neural network model (ANN) model was adopted to analyze significance of extraction parameters demonstrating high prediction levels of the β-carotene yield, experimentally confirming the maximum β-carotene content of 151.41 µg/mL at the optimal process condition. Extracted carotenoids in the optimal NADES extract have shown high stability during the storing period of 180 days. A switchable-hydrophilicity eutectic solvent system has been introduced as a successful way to recover extracted carotenoids from the NADES solvent. It was capable of precipitating 90% of carotenoids present in the extract. The proposed procedure is simple, easily scalable and has minimal impact on operators and the environment.

Indexed as

beta CaroteneCucurbitaDeep Eutectic SolventsChemical FractionationHydrophobic and Hydrophilic InteractionsNeural Networks, ComputerSolventsbeta CaroteneDeep Eutectic SolventsSolventsCarotenoidsNatural deep eutectic solventsSwitchable NADESUAE optimizationβ-Carotene

Identifiers

PMID34225213
PMCPMC8259401

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.