ArticleNeuroImage2021
Within node connectivity changes, not simply edge changes, influence graph theory measures in functional connectivity studies of the brain.
Article in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Using connectome-based predictive models to reveal the systems standardized tests and clinical symptoms are reflecting.Nature communications · 2026Article
- Interrogating functional connectivity of in vitro neural glia tissue model modulated through integrative control of matrix stiffness and a neurotrophic factor.Biomaterials · 2026Article
- Anatomic & functional brain atlases: connecting functional flexibility with fixed infrastructure.Brain structure & function · 2026Review
- A Transdiagnostic fMRI Dataset With 300+ Deeply Phenotyped Subjects Across Resting and Task States.medRxiv : the preprint server for health sciences · 2025Article
- Multimodal gradients unify local and global cortical organization.Nature communications · 2025Article
- Structure-function relationships across scales: implications for atlases.Frontiers in neuroscience · 2025Article
- Supervised brain node and network construction under voxel-level functional imaging.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Functional Brain Network Disruptions in Parkinson's Disease: Insights from Information Theory and Machine Learning.Diagnostics (Basel, Switzerland) · 2024Article
- Addressing Inconsistency in Functional Neuroimaging: A Replicable Data-Driven Multi-Scale Functional Atlas for Canonical Brain Networks.bioRxiv : the preprint server for biology · 2024Article
- Distinct alterations in white matter properties and organization related to maternal treatment initiation in neonates exposed to HIV but uninfected.Scientific reports · 2024Article
- Identifying canonical and replicable multi-scale intrinsic connectivity networks in 100k+ resting-state fMRI datasets.Human brain mapping · 2023Article
- Connectome-based machine learning models are vulnerable to subtle data manipulations.Patterns (New York, N.Y.) · 2023Article
- Brain-wide network analysis of resting-state neuromagnetic data.Human brain mapping · 2023Article
- Altered topological properties of functional brain networks in patients with first episode, late-life depression before and after antidepressant treatment.Frontiers in aging neuroscience · 2023Article
- A neuroimaging study of brain activity alterations in treatment-resistant depression after a dual target accelerated transcranial magnetic stimulation.Frontiers in psychiatry · 2023Article
- Inside information: Systematic within-node functional connectivity changes observed across tasks or groups.NeuroImage · 2022Article
- Future Directions for Chemosensory Connectomes: Best Practices and Specific Challenges.Frontiers in systems neuroscience · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Interest in understanding the organization of the brain has led to the application of graph theory methods across a wide array of functional connectivity studies. The fundamental basis of a graph is the node. Recent work has shown that functional nodes reconfigure with brain state. To date, all graph theory studies of functional connectivity in the brain have used fixed nodes. Here, using fixed-, group-, state-specific, and individualized- parcellations for defining nodes, we demonstrate that functional connectivity changes within the nodes significantly influence the findings at the network level. In some cases, state- or group-dependent changes of the sort typically reported do not persist, while in others, changes are only observed when node reconfigurations are considered. The findings suggest that graph theory investigations into connectivity contrasts between brain states and/or groups should consider the influence of voxel-level changes that lead to node reconfigurations; the fundamental building block of a graph.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.