ArticleProceedings of the National Academy of Sciences of the United States of America1988
Cell surface oligosaccharides participate in cohesion during aggregation of Dictyostelium discoideum.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 31 citations in OpenAlex.
- New insights into the N-glycomes ofBBA advances · 2025Article
- Mass spectrometric analysis of neutral and anionic N-glycans from a Dictyostelium discoideum model for human congenital disorder of glycosylation CDG IL.Journal of proteome research · 2013Article
- Carbohydrate cluster microarrays fabricated on three-dimensional dendrimeric platforms for functional glycomics exploration.Journal of proteome research · 2009Article
- Development of Dictyostelium discoideum is associated with alteration of fucosylated N-glycan structures.The Biochemical journal · 2009Article
- Cell adhesion in the life cycle of Dictyostelium.Experientia · 1995Review
- Dictyostelium discoideum lipids modulate cell-cell cohesion and cyclic AMP signaling.Molecular and cellular biology · 1991Article
- A glycosylation mutation affects cell fate in chimeras of Dictyostelium discoideum.Proceedings of the National Academy of Sciences of the United States of America · 1989Article
- Mapping of a cell-binding domain in the cell adhesion molecule gp80 of Dictyostelium discoideum.The Journal of cell biology · 1988Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Plasma membrane glycoproteins from Dictyostelium discoideum amoebae at three stages of early development were digested with Pronase and endoglycosidase H and fractionated by gel filtration. This gave three classes of glycans (polysaccharides, endoglycosidase H-resistant glycopeptides, and endoglycosidase H-released oligosaccharides), which were tested for their ability to block agglutination of amoebae from vegetative, aggregation (8-hr), and late-aggregation (13-hr) stages of development. The endoglycosidase H-resistant glycopeptides from 8-hr cells inhibited agglutination of disaggregated 8-hr cells but not vegetative or 13-hr cells. The 8-hr polysaccharide and endo H-sensitive oligosaccharides did not inhibit. The glycopeptides from 8-hr cells were resolved into five species by electrophoresis in borate-containing buffer. Two of these had agglutination-inhibiting activity, and three did not. None of the glycan fractions from vegetative or 13-hr cells inhibited agglutination of vegetative, 8-, or 13-hr cells. These data implicate specific cell surface glycans in aggregation-stage intercellular cohesion and suggest that both these glycans and receptors for them are developmentally regulated.
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