Evidence map›Paper›PMID 34224345›Full record

ArticleMicrobiology (Reading, England)2021

Phase-variable bacteria simultaneously express multiple capsules.

Samantha A Hsieh, David L Donermeyer, Stephen C Horvath, Paul M Allen

Open access · greenAbstract read
In one paragraph

Article in Microbiology (Reading, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Samantha A HsiehDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
David L DonermeyerDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Stephen C HorvathDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Paul M AllenDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Washington University in St. Louis · US

Funding

Immune Regulation by Bacteroides Polysaccharide CapsulesR21AI142257 · NIAID · WASHINGTON UNIVERSITY · PI ALLEN, PAUL M, MARTENS, ERIC C · 2019 to 2020
$502k
Initiation of symbiont-driven inflammatory bowel diseases by genetic mutations in T cells and antigen-presenting cellsF30DK114950 · NIDDK · WASHINGTON UNIVERSITY · PI BAI, SAMANTHA HSIEH · 2017 to 2019
$111k
NIAID NIH HHS R21 AI142257NIDDK NIH HHS F30 DK114950
6 · The paper itself

Abstract

Capsular polysaccharides (CPSs) protect bacteria from host and environmental factors. Many bacteria can express different CPSs and these CPSs are phase variable. For example,

Indexed as

Bacterial CapsulesBacteroides thetaiotaomicronGastrointestinal MicrobiomeHumansPolysaccharides, BacterialPolysaccharides, Bacterialcapsular polysaccharidemicrobiomephase-variable

Identifiers

PMID34224345
PMCPMC8489884
OpenAlexW3182997480

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.