Evidence map›Paper›PMID 34224298›Full record

ArticleAdipocyte2021

Regulation of adipose tissue lipolysis by ghrelin is impaired with high-fat diet feeding and is not restored with exercise.

Barbora Hucik, Andrew J Lovell, Evan M Hoecht, Daniel T Cervone, David M Mutch, David J Dyck

Open access · goldAbstract read
In one paragraph

Article in Adipocyte, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Systematic Review: Does Exercise Training Influence Ghrelin Levels?International journal of molecular sciences · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. LoweringInternational journal of molecular sciences · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Barbora HucikDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.
Andrew J LovellDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.
Evan M HoechtDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.
Daniel T CervoneDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.
David M MutchDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.ORCID 0000-0002-0908-7259
David J DyckDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.
University of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ghrelin is released from the stomach as an anticipatory signal prior to a meal and decreases immediately after. Previous research has shown that both acylated (AG) and unacylated (UnAG) ghrelin blunt adrenoreceptor-stimulated lipolysis in rat white adipose tissue (WAT)

Indexed as

Diet, High-FatLipolysisAdipose TissueAnimalsGhrelinObesityRatsGhrelinadiposeATOCexerciseGhrelinhigh-fat dietlipolysis

Identifiers

PMID34224298
PMCPMC8259717
OpenAlexW3179855248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.