Evidence map›Paper›PMID 34224238›Full record

ReviewJBRA assisted reproduction2021

The impact of congenital uterine abnormalities on pregnancy and fertility: a literature review.

Hossein Hosseinirad, Pouya Yadegari, Fatemeh Mohanazadeh Falahieh, Jahan Keivanlou Shahrestanaki, Bahareh Karimi, Nousha Afsharzadeh, Yousef Sadeghi

Open access · bronzeAbstract readReview
In one paragraph

Review in JBRA assisted reproduction, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Implantation Failure: Where to Look Up?Journal of clinical medicine · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Diagnosis of septate uterus.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022
    Article
  13. Treatment of septate uterus.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Hossein HosseiniradDepartment of Cell Biology and Anatomical Science, Faculty of Medicine, Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Pouya YadegariStudent Research Committee, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Fatemeh Mohanazadeh FalahiehSchool of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
Jahan Keivanlou ShahrestanakiStudent Research Committee, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Bahareh KarimiDepartment of Cell Biology and Anatomical Science, Faculty of Medicine, Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nousha AfsharzadehAzad Islamic University, Damghan Branch, Iran.
Yousef SadeghiDepartment of Anatomy and Neurosciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Victoria, Australia.
Shahid Beheshti University of Medical Sciences · IRIslamic Azad University, Damghan Branch · IRMashhad University of Medical Sciences · IRSabzevar University of Medical Sciences · IRUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital abnormalities of the uterus result primarily from embryological maldevelopment of the paramesonephric ducts and have been associated with pregnancy complications, reduced fertility, and other adverse fetal outcomes. While such abnormalities are rare, affected patients should be correctly managed to improve psychological, sexual, and reproductive outcomes. This review intends to elucidate the impact of congenital uterine abnormalities on fertility and pregnancy outcomes. We also present the available management methods and discuss the role of assisted reproductive technologies (ART) to benefit affected women. This review clearly shows that although these disorders are generally not lethal, they critically impact the patient's reproductive health. The fertility rate of patients with uterine congenital abnormalities depends on the severity of the condition. Reproductive endocrinologists and infertility specialists must be considered as active parts of the interdisciplinary treatment team for such patients. ART practices are reasonably successful at managing fertility problems of women with these abnormalities.

Indexed as

Urogenital AbnormalitiesUterusFemaleFertilityHumansPregnancyPregnancy OutcomeReproductive Techniques, Assistedcongenital abnormalitiesfertilityreproductive technologiesuterus

Identifiers

PMID34224238
PMCPMC8489822
OpenAlexW3177698882

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.