ArticleHead and neck pathology2022
Recurrent Primordial Odontogenic Tumor: Epithelium-Rich Variant.
Article in Head and neck pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Primordial Odontogenic Tumor: A Decade Post-Description Systematic Review.Head and neck pathology · 2024Pooled it
- Primordial odontogenic tumor: a case report of a rare entity in the Saudi population.BMC pediatrics · 2026Article
- Primordial Odontogenic Tumor Associated with Impacted Supernumerary Tooth: First Case Report and an Updated Review of Literature.Journal of maxillofacial and oral surgery · 2025Article
- New Insights into Ameloblastic Fibromas, Fibrodentinomas, and Fibro-Odontomas: Findings from an International Multicenter Study.Head and neck pathology · 2025Article
- Histopathological spectrum of primordial odontogenic tumor with co-existing dentigerous cyst: 1Diagnostic pathology · 2024Article
- Primordial Odontogenic Tumor; Archival Review of 19380 Cases in a 55-Year Retrospective Study.Asian Pacific journal of cancer prevention : APJCP · 2023Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primordial odontogenic tumor (POT) is a rare, mixed odontogenic neoplasm composed of spindled and stellate-shaped cells in myxoid stroma resembling dental papilla, surfaced by cuboidal-to-columnar odontogenic epithelium. Most POTs present in the posterior mandible as a well-demarcated radiolucency associated with a developing tooth in children and adolescents. POT is treated conservatively with no recurrences documented to-date. To describe the clinicopathological features of a recurrent POT. A 19-year-old female presented with an asymptomatic swelling, and panoramic radiograph revealed a multiloculated radiolucency in the mandibular body and ramus, with buccal and lingual perforation. The tumor was composed of plump spindle and stellate cells in a delicately collagenous and myxoid stroma, surfaced by columnar epithelial cells with reverse nuclear polarization. There was extensive epithelial proliferation forming invaginations within the tumor mass and organoid/enamel organ-like structures with enameloid-like deposits, dentinoid, and dystrophic calcifications. This was similar to the POT that had been excised four years prior from the same location. The patient underwent hemi-mandibulectomy and currently is free of disease at a thirteen-month follow-up. This report describes the first recurrent POT exhibiting extensive epithelial proliferation.
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Registered trials
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