ArticleInternational journal of epidemiology2022
Reflection on modern methods: statistical, policy and ethical implications of using age-standardized health indicators to quantify inequities.
Article in International journal of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
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- Understanding Mortality Data: A Step-by-Step Guide to CDC WONDER, Joinpoint Analysis, and Forecasting Models.Journal of epidemiology and global health · 2026Review
- Applying the Target Study Conceptual Model to Measure Racial and Ethnic Disparities in Hypertension Treatment Intensification.Epidemiology (Cambridge, Mass.) · 2026Article
- Exacerbation of racial disparities in COVID-19 outcomes by Alzheimer's disease and related dementias among nursing home residents.American journal of epidemiology · 2026Article
- Inequalities in cancer mortality between people with and without disability: A nationwide data linkage study of 10 million adults in Australia.PLoS medicine · 2026Article
- The Global Burden of Schizophrenia: Findings from the 2021 Global Burden of Diseases, Injuries, and Risk Factors Study.Schizophrenia bulletin open · 2026Article
- The health burden and racial-ethnic disparities of air pollution from the major oil and gas lifecycle stages in the United States.Science advances · 2025Article
- Global burden of esophageal diseases: a comprehensive analysis of disease trends and risk factors from 1990 to 2021.BMC gastroenterology · 2025Article
- Hyperglycemia and Obesity as the Key Drivers of Increased Colorectal Cancer Mortality in the North Africa and Middle East Region.Oman medical journal · 2025Article
- Incidence, prevalence and mortality of rheumatoid arthritis in Canterbury, Aotearoa New Zealand.Internal medicine journal · 2025Article
- The intersection of rurality and dementia prevalence in Australia for Aboriginal and Torres Strait Islander and non-Indigenous peoples.The Medical journal of Australia · 2025Article
- The burden of ischemic heart disease among women of childbearing age in China from 1990 to 2021, and projections for the next 15 years.BMC women's health · 2025Article
- Variable selection for causal inference, prediction, and descriptive research: a narrative review of recommendations.European heart journal open · 2025Review
- The Target Study: A Conceptual Model and Framework for Measuring Disparity.Sociological methods & research · 2025Article
- Global, regional, and national disability-adjusted life years and prevalence of lymphatic filariasis from 1990 to 2021: A trend and health inequality analysis based on the global burden of disease study 2021.PLoS neglected tropical diseases · 2025Article
- The Erosion of Healthcare and Scientific Integrity: A Growing Concern.Journal of healthcare leadership · 2025Review
- The burden of polycystic ovary syndrome-related infertility in 204 countries and territories, 1990-2021: an analysis of the global burden of disease study 2021.Frontiers in endocrinology · 2025Article
- Inequalities in disease burden and care quality of chronic obstructive pulmonary disease, 1990-2021: Findings from the Global Burden of Disease Study 2021.Journal of global health · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methods for calculating health indicators profoundly influence understanding of and action on population health and inequities. Age-standardization can be useful and is commonly applied to account for differences in age structures when comparing health indicators across groups. Age-standardized rates have well-acknowledged limitations, including that they are relative indices for comparison, and not accurate measures of actual rates where the age structures of groups diverge. This paper explores these limitations, and demonstrates alternative approaches through a case study quantifying mortality rates within the Aboriginal and Torres Strait Islander (Indigenous) population of Australia and inequities compared with the non-Indigenous population, over 2001-16. Applying the Australian Standard Population, the Aboriginal and Torres Strait Islander age-standardized mortality rate was more than double the crude mortality rate in 2001 and 2016, inflated through high weighting of older age groups. Despite divergent population age structures, age-standardized mortality rates remain a key policy metric for measuring progress in reducing Indigenous-non-Indigenous inequities in Australia. Focusing on outcomes age-standardized to the total population can obscure inequities, and denies Aboriginal and Torres Strait Islander peoples and communities valid, actionable information about their health and well-being. Age-specific statistics convey the true magnitude of health risks and highlight high-risk subgroups. When requiring standardization, standardizing to a population-specific standard (here, an Indigenous standard) generates metrics centred around and reflective of reality for the population of focus, supporting communities' self-determination to identify priorities and informing resource allocation and service delivery. The principles outlined here apply across populations, including Indigenous and other populations internationally.
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